# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA2405357 | F | Antiviral activity against Hepatitis C virus genotype 1b infected in human HuH7.5 cells after 3 days by luciferase reporter gene assay | Hepacivirus hominis | 2 | ALA2401666 | organism-based format | Scientific Literature | |
2. | ALA2405358 | F | Antiviral activity against Hepatitis C virus genotype 1a infected in human HuH7.5 cells after 3 days by luciferase reporter gene assay | Hepacivirus hominis | 2 | ALA2401666 | organism-based format | Scientific Literature | |
3. | ALA3122627 | A | Cytotoxicity against human HuH7 cells after 3 days by Cell Titre Glo assay | Homo sapiens | 6 | ALA3120092 | cell-based format | Scientific Literature | |
4. | ALA3122628 | F | Antiviral activity against Hepatitis C virus H77 genotype 1a infected in human HuH7 cells assessed as intrinsic antiviral potency after 72 hrs by luciferase reporter gene assay | Hepacivirus hominis | 41 | ALA3120092 | organism-based format | Scientific Literature | |
5. | ALA3122629 | F | Antiviral activity against Hepatitis C virus H77 genotype 1a infected in human HuH7 cells assessed as observed antiviral potency after 72 hrs by luciferase reporter gene assay | Hepacivirus hominis | 35 | ALA3120092 | organism-based format | Scientific Literature | |
6. | ALA3122630 | F | Antiviral activity against Hepatitis C virus Con1 genotype 1b infected in human HuH7 cells after 72 hrs by luciferase reporter gene assay | Hepacivirus hominis | 6 | ALA3120092 | organism-based format | Scientific Literature | |
7. | ALA3122631 | A | Fraction unbound in cell culture medium at 2 uM at pH 7.4 by equilibrium dialysis method | 23 | ALA3120092 | assay format | Scientific Literature | ||
8. | ALA3122632 | A | Cytotoxicity against human MT4 cells after 5 days by Cell Titre Glo assay | Homo sapiens | 42 | ALA3120092 | cell-based format | Scientific Literature | |
9. | ALA3122633 | F | Antiviral activity against HCV genotype 1b infected in human patient assessed as log10 reduction in viral RNA in plasma at 750 mg/kg, bid after 3 days | Hepacivirus hominis | 1 | ALA3120092 | organism-based format | Scientific Literature | |
10. | ALA4478794 | B | Allosteric inhibition of HCV genotype 1b NS5A infected in human l389lucubi- neo/NS3-375.1-containing Huh7ET cells assessed as RNA replication/translation after 4 days by luciferase reporter gene assay | Hepatitis C virus subtype 1b | 20 | ALA4477222 | assay format | Scientific Literature | |
11. | ALA4478796 | A | Cytotoxicity against human Huh7ET cells assessed as reduction in cell viability after 4 days | Homo sapiens | 20 | ALA4477222 | cell-based format | Scientific Literature | |
12. | ALA4478797 | B | Allosteric inhibition of HCV genotype 1a NS5A infected in human W11.8 cells assessed as reduction in viral RNA replication after 4 days by ELISA | Hepatitis C virus subtype 1a | 20 | ALA4477222 | cell-based format | Scientific Literature | |
13. | ALA4478798 | A | Cytotoxicity against human W11.8 cells assessed as reduction in cell viability after 4 days | Homo sapiens | 20 | ALA4477222 | cell-based format | Scientific Literature | |
14. | ALA4478799 | B | Allosteric inhibition of HCV genotype 1b NS5A infected in human l389lucubi- neo/NS3-375.1-containing Huh7ET cells assessed as RNA replication/translation after 4 days in presence of 40% human serum by luciferase reporter gene assay | Hepatitis C virus subtype 1b | 2 | ALA4477222 | assay format | Scientific Literature | |
15. | ALA4478802 | B | Inhibition of HCV genotype 2a NS5A | Hepatitis C virus subtype 2a | 2 | ALA4477222 | single protein format | Scientific Literature | |
16. | ALA4478803 | B | Inhibition of HCV genotype 1a NS5B L419M mutant | Hepatitis C virus subtype 1a | 2 | ALA4477222 | single protein format | Scientific Literature | |
17. | ALA4478804 | B | Inhibition of HCV genotype 1a NS5B L419I mutant | Hepatitis C virus subtype 1a | 2 | ALA4477222 | single protein format | Scientific Literature | |
18. | ALA4478805 | B | Inhibition of HCV genotype 1a NS5B M423I mutant | Hepatitis C virus subtype 1a | 2 | ALA4477222 | single protein format | Scientific Literature | |
19. | ALA4478806 | B | Inhibition of HCV genotype 1a NS5B M423T mutant | Hepatitis C virus subtype 1a | 2 | ALA4477222 | single protein format | Scientific Literature | |
20. | ALA4478807 | B | Inhibition of HCV genotype 1a NS5B M423V mutant | Hepatitis C virus subtype 1a | 2 | ALA4477222 | single protein format | Scientific Literature |