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# Aladdin ID Assay Type Description Organism Compounds Reference BAO Format Source 1. ALA1781103 Functional Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assay Homo sapiens 41 ALA1777763 cell-based format Scientific Literature 2. ALA1781104 Functional Agonist activity at human GPR119 expressed in HEK293 cells assessed as maximal stimulation of cMAP level by cell-based cAMP assay relative to 21 Homo sapiens 33 ALA1777763 cell-based format Scientific Literature 3. ALA1781105 Functional Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as stimulation of cMAP level by cell-based cAMP assay Mus musculus 30 ALA1777763 cell-based format Scientific Literature 4. ALA1781106 Functional Agonist activity at mouse GPR119 expressed in HEK293 cells assessed as maximal stimulation of cMAP level by cell-based cAMP assay relative to 21 Mus musculus 30 ALA1777763 cell-based format Scientific Literature 5. ALA1781107 Functional Antidiabetic activity in overnight fasted mouse model assessed as blood glucose level at 3 mg/kg, po followed by 30 mins after administered 3 g/kg, po glucose by oral glucose tolerance test (Rvb = 100 %) Mus musculus 8 ALA1777763 organism-based format Scientific Literature 6. ALA1781108 ADME Plasma concentration in mouse at 3 mg/kg, po after 1 hr Mus musculus 8 ALA1777763 organism-based format Scientific Literature 7. ALA1781109 ADME AUC (0 to 6 hrs) in rat at 10 mg/kg, po Rattus norvegicus 7 ALA1777763 organism-based format Scientific Literature 8. ALA1781110 ADME Inhibition of CYP3A4 1 ALA1777763 single protein format Scientific Literature 9. ALA1781111 ADME Inhibition of CYP2D6 1 ALA1777763 single protein format Scientific Literature 10. ALA1781112 ADME Inhibition of CYP2C9 1 ALA1777763 single protein format Scientific Literature 11. ALA1781113 Binding Inhibition of human PXR transfected in HepG2 cells at 10 uM Homo sapiens 1 ALA1777763 cell-based format Scientific Literature 12. ALA1781114 Binding Inhibition of human ERG at 10 uM Homo sapiens 1 ALA1777763 single protein format Scientific Literature 13. ALA1781115 Binding Inhibition of GPCR-1 at 10 uM 1 ALA1777763 single protein format Scientific Literature 14. ALA1781116 ADME AUC (0 to 24 hrs) in monkey at 3 mg/kg, po Macaca mulatta 1 ALA1777763 organism-based format Scientific Literature 15. ALA1781117 ADME Cmax in monkey at 3 mg/kg, po Macaca mulatta 1 ALA1777763 organism-based format Scientific Literature 16. ALA1781118 ADME Tmax in monkey at 3 mg/kg, po Macaca mulatta 1 ALA1777763 organism-based format Scientific Literature 17. ALA1781119 Toxicity Genotoxicity in Salmonella Typhimurium by Ames test Salmonella enterica subsp. enterica serovar Typhimurium 1 ALA1777763 organism-based format Scientific Literature 18. ALA1781120 Functional Antidiabetic activity in laen mouse model assessed as reduction in blood glucose level at 3 mg/kg, po up to 60 mins by oral glucose tolerance test Mus musculus 1 ALA1777763 organism-based format Scientific Literature 19. ALA1781121 Functional Antidiabetic activity in laen mouse model assessed as reduction in blood glucose level at 10 mg/kg, po up to 60 mins by oral glucose tolerance test Mus musculus 1 ALA1777763 organism-based format Scientific Literature 20. ALA1781122 Functional Antidiabetic activity in laen mouse model assessed as reduction in blood glucose level at 30 mg/kg, po up to 60 mins by oral glucose tolerance test Mus musculus 2 ALA1777763 organism-based format Scientific Literature