| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA619870 | F | Inhibition of oxidation of arachidonic acid by human 5-Lipoxygenase using spectrophotometric assay | Homo sapiens | 10 | assay format | Scientific Literature | ||
| 2. | ALA618012 | B | Potency to inhibit oxidation of arachidonic acid by recombinant human 5-lipoxygenase | 52 | single protein format | Scientific Literature | |||
| 3. | ALA622829 | A | Maximum concentration of unchanged drug in rat plasma in the period 0-24 hr after dosing | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
| 4. | ALA874448 | A | Bioavailability in rat (Sprague-Dawley) (male) | Rattus norvegicus | 4 | organism-based format | Scientific Literature | ||
| 5. | ALA702328 | F | Compound was evaluated for production of leukotriene B4 in human whole blood (HWB) activated with ionophore A-23187. | Homo sapiens | 11 | organism-based format | Scientific Literature | ||
| 6. | ALA701221 | F | Compound was tested for the inhibition of LTB4 production in human whole blood (HWB) | Homo sapiens | 45 | organism-based format | Scientific Literature | ||
| 7. | ALA878772 | F | Compound was evaluated for production of leukotriene B4 in Ca+2 -ionophore -activated human polymorphonuclear (HPMN) leukocytes. | Homo sapiens | 12 | organism-based format | Scientific Literature | ||
| 8. | ALA767676 | F | Test inhibition of LTB4 production in human peripheral blood polymorphonuclear leukocytes (HPMN) | Homo sapiens | 53 | organism-based format | Scientific Literature | ||
| 9. | ALA5247062 | A | Oral bioavailability in rat | Rattus norvegicus | 16 | organism-based format | Scientific Literature | ||
| 10. | ALA5247076 | F | Inhibition of Leukotriene B4 production in human whole blood | Homo sapiens | 6 | organism-based format | Scientific Literature | ||
| 11. | ALA5247077 | A | Drug metabolism in rat liver microsomes assessed as metabolite formation incubated for 1 hrs | Rattus norvegicus | 2 | microsome format | Scientific Literature | ||
| 12. | ALA5247078 | A | Cmax in rat plasma at 20 mg/kg, po | Rattus norvegicus | 3 | organism-based format | Scientific Literature | ||
| 13. | ALA5247080 | B | Inhibition of human 5-LO expressed in Sf9 cells by spectrophotometric assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 14. | ALA5247081 | F | Inhibition of Leukotriene B4 production in human blood Polymorphonuclear neutrophil cells | Homo sapiens | 6 | tissue-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!