# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA651145 | Binding | Inhibition of beta-3 adrenergic receptor GDP binding in rat brown adipose tissue on oral administration relative to isoprenaline | Rattus norvegicus | 11 | ALA1126035 | tissue-based format | Scientific Literature | |
2. | ALA651146 | Binding | Dose necessary to produce 50% of the isoprenaline effect to inhibit GDP binding to beta-3 adrenergic receptor in brown adipose tissue (BAT mitochondria) of rats after subcutaneous administration. | 28 | ALA1126035 | mitochondrion format | Scientific Literature | ||
3. | ALA840718 | Functional | Ratio of the dose (D500,peroral administration) elevating the rat heart rate to 500 bpm to the GDP ED50. | 13 | ALA1126035 | organism-based format | Scientific Literature | ||
4. | ALA840720 | Functional | Ratio of the dose raising the rat heart rate to 500bpm, to ED50 for inhibition of GDP binding to beta-3 adrenergic receptor | Rattus norvegicus | 21 | ALA1126035 | tissue-based format | Scientific Literature | |
5. | ALA4303805 | Functional | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of Caco-2 cells at 10 uM after 48 hours by high content imaging | Homo sapiens | 5,612 | ALA4303101 | organism-based format | SARS-CoV-2 Screening Data 2020-21 | |
6. | ALA4495582 | Functional | SARS-CoV-2 3CL-Pro protease inhibition percentage at 20µM by FRET kind of response from peptide substrate | Severe acute respiratory syndrome coronavirus 2 | 7,212 | ALA4495564 | assay format | SARS-CoV-2 Screening Data 2020-21 | |
7. | ALA4513082 | Functional | Antiviral activity determined as inhibition of SARS-CoV-2 induced cytotoxicity of VERO-6 cells at 10 uM after 48 hours exposure to 0.01 MOI SARS CoV-2 virus by high content imaging | Chlorocebus sabaeus | 7,212 | ALA4495565 | organism-based format | SARS-CoV-2 Screening Data 2020-21 |