| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3088608 | ADME | Metabolic stability in mouse serum assessed as compound remaining at 0.1 mM after 1 hr by HPLC analysis | Mus musculus | 29 | ALA3085624 | assay format | Scientific Literature | |
| 2. | ALA3088609 | Binding | Binding affinity to rat KISS1R | Rattus norvegicus | 29 | ALA3085624 | single protein format | Scientific Literature | |
| 3. | ALA3088610 | Binding | Binding affinity to human KISS1R expressed in CHO cell membranes | Homo sapiens | 29 | ALA3085624 | cell-based format | Scientific Literature | |
| 4. | ALA3088611 | Functional | Agonist activity at recombinant human KISS1R expressed in CHO cells assessed as intracellular calcium mobilization incubated for 30 mins at 37 degC and 30 mins at room temperature by Fluo-4 NW staining-based FLIPR assay relative to Metastin (45 to 54) | Homo sapiens | 28 | ALA3085624 | cell-based format | Scientific Literature | |
| 5. | ALA4332252 | Functional | Agonist activity at human KISS1R expressed in CHO cells assessed as increase in calcium mobilization measured at 2 secs interval for 2 mins by fluo-4 NW dye based FLIPR assay | Homo sapiens | 28 | ALA4330106 | cell-based format | Scientific Literature | |
| 6. | ALA4332262 | Physicochemical | Retention time of the compound by reverse-phase HPLC method | 26 | ALA4330106 | small-molecule physicochemical format | Scientific Literature |
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