# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3090730 | Binding | Activation of NFkappaB in mouse BMDM assessed as degradation of IkappaBalpha at 10 ug/ml after 15 to 30 mins by Western blotting | Mus musculus | 1 | ALA3085690 | single protein format | Scientific Literature | |
2. | ALA3090731 | Binding | Activation of NFkappaB p65 in mouse BMDM assessed as phosphorylation at 10 ug/ml after 15 to 30 mins by Western blotting | Mus musculus | 2 | ALA3085690 | single protein format | Scientific Literature | |
3. | ALA3090732 | Binding | Activation of JNK in mouse BMDM assessed as phosphorylation at 10 ug/ml by Western blotting | Mus musculus | 1 | ALA3085690 | assay format | Scientific Literature | |
4. | ALA3090981 | Binding | Activation of ERK1/2 in mouse BMDM assessed as phosphorylation at 10 ug/ml after 15 to 30 mins by Western blotting | Mus musculus | 1 | ALA3085690 | protein format | Scientific Literature | |
5. | ALA3090982 | Binding | Activation of p38 kinase in mouse BMDM assessed as phosphorylation at 10 ug/ml by Western blotting | Mus musculus | 1 | ALA3085690 | protein format | Scientific Literature | |
6. | ALA3091013 | Functional | Increase of CXCL2 production in mouse BMDM after 6 hrs by ELISA in presence of NFkappaB inhibitor Bay11-7082 | Mus musculus | 1 | ALA3085690 | assay format | Scientific Literature | |
7. | ALA3091014 | Functional | Increase of CXCL2 production in mouse BMDM after 6 hrs by ELISA in presence of JNK inhibitor SP600125 | Mus musculus | 1 | ALA3085690 | assay format | Scientific Literature | |
8. | ALA3091015 | Functional | Increase of CXCL2 production in mouse BMDM after 6 hrs by ELISA in presence of MEK1/2 inhibitor U0126 | Mus musculus | 1 | ALA3085690 | assay format | Scientific Literature | |
9. | ALA3091016 | Functional | Increase of CXCL2 production in mouse BMDM after 6 hrs by ELISA in presence of KN-62 | Mus musculus | 1 | ALA3085690 | assay format | Scientific Literature | |
10. | ALA3091017 | Functional | Increase of CXCL2 production in mouse BMDM after 6 hrs by ELISA in presence of p38 MAPK inhibitor SB-202190 | Mus musculus | 1 | ALA3085690 | assay format | Scientific Literature | |
11. | ALA3091018 | Functional | Increase of CXCL2 production in mouse BMDM after 6 hrs by ELISA in presence of CD14 Ab | Mus musculus | 1 | ALA3085690 | assay format | Scientific Literature | |
12. | ALA3091019 | Functional | Increase of CXCL2 production in mouse BMDM after 6 hrs by ELISA in presence of WRW4 | Mus musculus | 1 | ALA3085690 | assay format | Scientific Literature | |
13. | ALA3091020 | Functional | Increase of CXCL2 production in mouse BMDM after 6 hrs by ELISA in presence of pertussis toxin | Mus musculus | 1 | ALA3085690 | assay format | Scientific Literature | |
14. | ALA3091021 | Functional | Downregulation of TLR4/MD2 complex in plasma membrane in mouse RAW264.7 cells relative to LPS | Mus musculus | 1 | ALA3085690 | cell-based format | Scientific Literature | |
15. | ALA3091022 | Functional | Increase of CXCL2 production in mouse BMDM after 6 hrs by ELISA in presence of TLR4/MD2 Ab | Mus musculus | 1 | ALA3085690 | assay format | Scientific Literature | |
16. | ALA3091023 | Functional | Inhibition of PGN-induced TNFalpha production in mouse RAW264.7 cells 2 to 50 ug/ml after 6 hrs by ELISA | Mus musculus | 1 | ALA3085690 | cell-based format | Scientific Literature | |
17. | ALA3091024 | Functional | Inhibition of LTA-induced TNFalpha production in mouse RAW264.7 cells 2 to 50 ug/ml after 6 hrs by ELISA | Mus musculus | 1 | ALA3085690 | cell-based format | Scientific Literature | |
18. | ALA3091025 | Functional | Inhibition of LPS-induced nitric oxide production in mouse RAW264.7 cells 2 to 50 ug/ml after 6 hrs by ELISA | Mus musculus | 1 | ALA3085690 | cell-based format | Scientific Literature | |
19. | ALA3091026 | Functional | Inhibition of LPS-induced IL-6 production in mouse RAW264.7 cells 2 to 50 ug/ml after 6 hrs by ELISA | Mus musculus | 1 | ALA3085690 | cell-based format | Scientific Literature | |
20. | ALA3091027 | Functional | Inhibition of LPS-induced TNFalpha production in mouse RAW264.7 cells 2 to 50 ug/ml after 6 hrs by ELISA | Mus musculus | 1 | ALA3085690 | cell-based format | Scientific Literature |