| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3088814 | F | Induction of apoptosis in human MDA-MB-231 cells after 24 hrs using FITC-annexin V and propidium iodide staining by flow cytometry | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA3088815 | T | Toxicity in human MDA-MB-231 cells xenografted nude mouse assessed as change body weight at 5 mg/kg, ip administered 5 days per week for 10 days | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 3. | ALA3088816 | F | Antitumor activity against human MDA-MB-231 cells xenografted in nude mouse assessed as inhibition of tumor growth at 5 mg/kg, ip administered 5 days per week for 10 days | Homo sapiens | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA3088823 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as caspase3 activation after 48 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA3088824 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as PARP cleavage after 48 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA3088825 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as downregulation of p65 NF-kappaB level at 2.5 to 10 uM after 48 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 7. | ALA3088826 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as upregulation of Bax level at 2.5 to 10 uM after 48 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 8. | ALA3088827 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as downregulation of Bcl2 level at 2.5 to 10 uM after 48 hrs by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 9. | ALA3088828 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as live cells at 10 uM after 24 hrs using FITC-annexin V and propidium iodide staining by flow cytometry (Rvb = 83.45 to 89.30 %) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 10. | ALA3088829 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as late apoptotic cells at 10 uM after 24 hrs using FITC-annexin V and propidium iodide staining by flow cytometry (Rvb = 5.5 to 11.0 %) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 11. | ALA3088830 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as early apoptotic cells at 10 uM after 24 hrs using FITC-annexin V and propidium iodide staining by flow cytometry (Rvb = 4.55 to 4.85 %) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 12. | ALA3088831 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as dead cells at 10 uM after 24 hrs using FITC-annexin V and propidium iodide staining by flow cytometry (Rvb = 0.3 to 1.00 %) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 13. | ALA3088832 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as live cells at 5 uM after 24 hrs using FITC-annexin V and propidium iodide staining by flow cytometry (Rvb = 83.45 to 89.30 %) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA3088833 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as early apoptotic cells at 5 uM after 24 hrs using FITC-annexin V and propidium iodide staining by flow cytometry (Rvb = 4.55 to 4.85 %) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 15. | ALA3088834 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as late apoptotic cells at 5 uM after 24 hrs using FITC-annexin V and propidium iodide staining by flow cytometry (Rvb = 5.5 to 11.0 %) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 16. | ALA3088835 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as dead cells at 5 uM after 24 hrs using FITC-annexin V and propidium iodide staining by flow cytometry (Rvb = 0.3 to 1.00 %) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 17. | ALA3088836 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as live cells at 1 uM after 24 hrs using FITC-annexin V and propidium iodide staining by flow cytometry (Rvb = 83.45 to 89.30 %) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 18. | ALA3088837 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as early apoptotic cells at 1 uM after 24 hrs using FITC-annexin V and propidium iodide staining by flow cytometry (Rvb = 4.55 to 4.85 %) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 19. | ALA3088838 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as late apoptotic cells at 1 uM after 24 hrs using FITC-annexin V and propidium iodide staining by flow cytometry (Rvb = 5.5 to 11.0 %) | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 20. | ALA3088839 | A | Growth inhibition of human HMEC cells after 48 hrs | Homo sapiens | 6 | cell-based format | Scientific Literature |
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