# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3090517 | F | Potentiation of 5-FU-induced cytotoxicity against human SW620 cells assessed as reduction in compound IC50 at 30 uM after 72 hrs by MTT assay relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
2. | ALA3090749 | F | Potentiation of 5-FU-induced cytotoxicity against human HT-29 cells assessed as reduction in compound IC50 at 30 uM after 72 hrs by MTT assay relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
3. | ALA3090750 | A | Effect on 5-FU-induced cytotoxicity against human HaCaT cells at 30 uM after 72 hrs by MTT assay | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
4. | ALA3090751 | F | Cytotoxicity against human SW620 cells at 1 to 100 uM after 72 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
5. | ALA3090752 | F | Cytotoxicity against human HT-29 cells at 1 to 100 uM after 72 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
6. | ALA3090753 | A | Cytotoxicity against human HaCaT cells at 1 to 100 uM after 72 hrs by MTT assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
7. | ALA3090755 | B | Binding affinity to human recombinant UP1-R1P binary complex expressed in Escherichia coli Rosetta (DE3) at 150 uM R1P by isothermal titration calorimetric analysis | Homo sapiens | 7 | assay format | Scientific Literature | ||
8. | ALA3090756 | B | Binding affinity to human recombinant UP1-R1P binary complex expressed in Escherichia coli Rosetta (DE3) at 50 uM R1P by isothermal titration calorimetric analysis | Homo sapiens | 7 | assay format | Scientific Literature | ||
9. | ALA3090757 | B | Binding affinity to human recombinant UP1-inorganic phosphate binary complex expressed in Escherichia coli Rosetta (DE3) by isothermal titration calorimetric analysis | Homo sapiens | 6 | assay format | Scientific Literature | ||
10. | ALA3090758 | B | Binding affinity to human recombinant UP1 expressed in Escherichia coli Rosetta (DE3) by isothermal titration calorimetric analysis | Homo sapiens | 6 | assay format | Scientific Literature | ||
11. | ALA3090759 | B | Inhibition of human thymidine phosphorylase | Homo sapiens | 6 | single protein format | Scientific Literature | ||
12. | ALA3090760 | B | Uncompetitive inhibition of human recombinant UP1 expressed in Escherichia coli Rosetta (DE3) using inorganic phosphate as substrate by Lineweaver-Burk plot analysis | Homo sapiens | 5 | assay format | Scientific Literature | ||
13. | ALA3090763 | B | Competitive inhibition of human recombinant UP1 expressed in Escherichia coli Rosetta (DE3) using URD as substrate by Lineweaver-Burk plot analysis | Homo sapiens | 5 | assay format | Scientific Literature | ||
14. | ALA3090766 | B | Time dependent inhibition of human recombinant UP1 expressed in Escherichia coli Rosetta (DE3) using URD and inorganic phosphate as substrate at 1 uM by spectrophotometric analysis | Homo sapiens | 6 | assay format | Scientific Literature | ||
15. | ALA3090767 | B | Inhibition of human recombinant UP1 expressed in Escherichia coli Rosetta (DE3) using URD and inorganic phosphate as substrate at 1 uM after 60 seconds by spectrophotometric analysis relative to control | Homo sapiens | 22 | assay format | Scientific Literature |