# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3088712 | F | Induction of apoptosis in mouse L1210 cells assessed as inhibition of caspase-8 activity at CC50 after 12 hrs by fluorescence assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
2. | ALA3088713 | F | Induction of apoptosis in mouse L1210 cells assessed as inhibition of caspase-8 activity at CC50 after 4 hrs by fluorescence assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
3. | ALA3088714 | F | Induction of apoptosis in mouse L1210 cells assessed as inhibition of caspase-3 activity at CC50 after 4 hrs by fluorescence assay | Mus musculus | 1 | cell-based format | Scientific Literature | ||
4. | ALA3088715 | F | Induction of apoptosis in mouse L1210 cells assessed as increase of caspase-3 activity at CC50 after 12 hrs by fluorescence assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
5. | ALA3088716 | F | Induction of apoptosis in mouse L1210 cells assessed as increase of caspase-12 activity at CC50 after 4 hrs by fluorescence assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
6. | ALA3088717 | F | Induction of apoptosis in mouse L1210 cells assessed as increase of caspase-3 activity at CC50 after 4 hrs by fluorescence assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
7. | ALA3088718 | F | Induction of apoptosis in mouse L1210 cells assessed as ROS production at CC70 after 4 hrs using DCFH-DA staining by fluorescence assay relative to control | Mus musculus | 2 | cell-based format | Scientific Literature | ||
8. | ALA3088719 | F | Induction of apoptosis in mouse L1210 cells assessed as ROS production at CC50 after 4 hrs using DCFH-DA staining by fluorescence assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
9. | ALA3088720 | F | Induction of apoptosis in mouse L1210 cells assessed as loss of mitochondrial membrane potential at CC70 after 4 hrs using JC-1 staining by fluorescence assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
10. | ALA3088721 | F | Induction of apoptosis in mouse L1210 cells assessed as loss of mitochondrial membrane potential at CC50 after 4 hrs using JC-1 staining by fluorescence assay | Mus musculus | 2 | cell-based format | Scientific Literature | ||
11. | ALA3088722 | F | Induction of apoptosis in mouse L1210 cells assessed as viable cells at CC50 after 24 hrs using Annexin-V-FITC and propidium iodide staining by flow cytometry analysis (Rvb = 96.01%) | Mus musculus | 2 | cell-based format | Scientific Literature | ||
12. | ALA3088723 | F | Induction of apoptosis in mouse L1210 cells assessed as early apoptotic cells at CC50 after 24 hrs using Annexin-V-FITC and propidium iodide staining by flow cytometry analysis (Rvb = 1.17%) | Mus musculus | 2 | cell-based format | Scientific Literature | ||
13. | ALA3088724 | F | Induction of apoptosis in mouse L1210 cells assessed as late apoptotic cells at CC50 after 24 hrs using Annexin-V-FITC and propidium iodide staining by flow cytometry analysis (Rvb = 1.95%) | Mus musculus | 2 | cell-based format | Scientific Literature | ||
14. | ALA3088725 | F | Induction of apoptosis in mouse L1210 cells assessed as necrotic cells at CC50 after 24 hrs using Annexin-V-FITC and propidium iodide staining by flow cytometry analysis (Rvb = 0.87%) | Mus musculus | 2 | cell-based format | Scientific Literature | ||
15. | ALA3089137 | F | Induction of apoptosis in mouse L1210 cells assessed as DNA fragmentation at CC50 after 24 hrs using acridine orange/ethidium bromide staining by fluorescence microscopic analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
16. | ALA3089138 | F | Cell cycle arrest in mouse B16F10 cells assessed as cell fragmentation at CC50 after 24 hrs using propidium iodide staining by flow cytometry analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
17. | ALA3089139 | F | Cell cycle arrest in mouse L1210 cells assessed as cell fragmentation at CC50 after 24 hrs using propidium iodide staining by flow cytometry analysis | Mus musculus | 2 | cell-based format | Scientific Literature | ||
18. | ALA3089140 | F | Selectivity index, ratio of CC50 for african green monkey Vero cells to CC50 for human MDA-MB-231 cells | 8 | cell-based format | Scientific Literature | |||
19. | ALA3089141 | F | Selectivity index, ratio of CC50 for african green monkey Vero cells to CC50 for mouse B16F10 cells | 8 | cell-based format | Scientific Literature | |||
20. | ALA3089142 | F | Selectivity index, ratio of CC50 for african green monkey Vero cells to CC50 for human CCRF-CEM cells | 5 | cell-based format | Scientific Literature |