# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3089981 | F | Antiviral activity against Herpes simplex virus 2 G infected in HEL cells assessed as inhibition of virus-induced cytopathicity | Human alphaherpesvirus 2 | 3 | ALA3085731 | organism-based format | Scientific Literature | |
2. | ALA3089982 | F | Antiviral activity against Herpes simplex virus 1 KOS infected in HEL cells assessed as inhibition of virus-induced cytopathicity | Human alphaherpesvirus 1 | 3 | ALA3085731 | organism-based format | Scientific Literature | |
3. | ALA3089983 | F | Antiviral activity against thymidine kinase-deficient ACV-resistant Herpes simplex virus 1 KOS infected in HEL cells assessed as inhibition of virus-induced cytopathicity | Human alphaherpesvirus 1 | 3 | ALA3085731 | organism-based format | Scientific Literature | |
4. | ALA3089984 | P | Chemical stability of the compound in sodium phosphate buffer at pH 3.2 after 6 hrs | 2 | ALA3085731 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA3089987 | A | Prodrug conversion assessed as dipeptidyl peptidase 4-mediated hydrolyis in human serum at 25 uM after 24 hrs by HPLC analysis in presence of vildagliptin | Homo sapiens | 2 | ALA3085731 | single protein format | Scientific Literature | |
6. | ALA3089990 | A | Prodrug conversion assessed as human dipeptidyl peptidase 4-mediated ACV formation at 50 uM after 24 hrs by HPLC analysis | Homo sapiens | 3 | ALA3085731 | single protein format | Scientific Literature | |
7. | ALA3089991 | A | Prodrug conversion assessed as dipeptidyl peptidase 4-mediated Val-ACV formation in bovine serum at 50 uM after 15 mins by HPLC analysis | Bos taurus | 1 | ALA3085731 | single protein format | Scientific Literature | |
8. | ALA3089992 | A | Prodrug conversion assessed as dipeptidyl peptidase 4-mediated Val-ACV formation in human serum at 50 uM after 15 mins by HPLC analysis | Homo sapiens | 1 | ALA3085731 | single protein format | Scientific Literature | |
9. | ALA3089993 | A | Prodrug conversion assessed as human dipeptidyl peptidase 4-mediated Val-ACV formation at 50 uM after 24 hrs by HPLC analysis | Homo sapiens | 1 | ALA3085731 | single protein format | Scientific Literature | |
10. | ALA3089994 | A | Prodrug conversion in PBS buffer assessed as ACV formation at 50 uM after 24 hrs by HPLC analysis | 3 | ALA3085731 | assay format | Scientific Literature | ||
11. | ALA3089998 | P | Solubility of the compound in deionized water at pH 5.5 after overnight incubation by HPLC analysis | 3 | ALA3085731 | small-molecule physicochemical format | Scientific Literature |