| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3096570 | Binding | Agonist activity at GPR39 in rat INS-1 cells assessed as effect on glucose-stimulated insulin secretion | Rattus norvegicus | 1 | ALA3091456 | cell-based format | Scientific Literature | |
| 2. | ALA3096571 | Binding | Agonist activity at GPR39 in human islets assessed as 11.2 mM glucose-stimulated insulin secretion up to 10 uM after 1 hr | Homo sapiens | 1 | ALA3091456 | single protein format | Scientific Literature | |
| 3. | ALA3096572 | Binding | Agonist activity at GPR39 in human islets assessed as 2.8 mM glucose-stimulated insulin secretion up to 10 uM after 0.75 hrs | Homo sapiens | 1 | ALA3091456 | single protein format | Scientific Literature | |
| 4. | ALA3096573 | Functional | Agonist activity at GPR39 in human HT-29 cells assessed as cAMP accumulation | Homo sapiens | 1 | ALA3091456 | cell-based format | Scientific Literature | |
| 5. | ALA3096574 | Functional | Agonist activity at GPR39 in human HT-29 cells assessed as intracellular Ca2+ mobilization after 72 hrs by FLIPR assay in presence of siRNA | Homo sapiens | 1 | ALA3091456 | cell-based format | Scientific Literature | |
| 6. | ALA3096575 | Functional | Agonist activity at GPR39 in human HT-29 cells assessed as increase in intracellular Ca2+ mobilization after 72 hrs by FLIPR assay | Homo sapiens | 1 | ALA3091456 | cell-based format | Scientific Literature | |
| 7. | ALA3096576 | Binding | Inhibition of PDE3B (unknown origin) | Homo sapiens | 1 | ALA3091456 | single protein format | Scientific Literature | |
| 8. | ALA3096577 | Binding | Inhibition of PDE3a (unknown origin) | Homo sapiens | 1 | ALA3091456 | single protein format | Scientific Literature | |
| 9. | ALA3096578 | Functional | Agonist activity at recombinant human GPR39 expressed in CHO-K1 cells assessed as increase of Zn2+-induced cAMP production preincubated for 30 mins measured after 60 mins relative to Zn+2 | Homo sapiens | 4 | ALA3091456 | cell-based format | Scientific Literature | |
| 10. | ALA3096579 | Binding | Agonist activity at recombinant human GPR39 expressed in CHO-K1 cells assessed as increase of Zn2+-induced intracellular Ca+2 mobilization after 1 hr by Fluo-4 No staining-based FLIPR assay relative to Zn+2 | Homo sapiens | 4 | ALA3091456 | cell-based format | Scientific Literature | |
| 11. | ALA3096580 | Functional | Agonist activity at recombinant human GPR39 expressed in CHO-K1 cells assessed as increase of Zn2+-induced cAMP production preincubated for 30 mins measured after 60 mins | Homo sapiens | 4 | ALA3091456 | cell-based format | Scientific Literature | |
| 12. | ALA3096581 | ADME | Apparent permeability across MDCK cells | Canis lupus familiaris | 1 | ALA3091456 | cell-based format | Scientific Literature | |
| 13. | ALA3096582 | Binding | Agonist activity at recombinant human GPR39 expressed in CHO-K1 cells assessed as increase of Zn2+-induced intracellular Ca+2 mobilization after 1 hr by Fluo-4 No staining-based FLIPR assay | Homo sapiens | 4 | ALA3091456 | cell-based format | Scientific Literature | |
| 14. | ALA5134916 | Functional | Agonist activity at human GPR39 receptor expressed in CHO cells assessed as increase in ca2+ flux | Homo sapiens | 17 | ALA5131482 | cell-based format | Scientific Literature | |
| 15. | ALA5134917 | Functional | Agonist activity at human GPR39 receptor expressed in CHO cells assessed as increase in ca2+ flux relative to Zn2+ | Homo sapiens | 11 | ALA5131482 | cell-based format | Scientific Literature |
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