# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3095525 | T | Toxicity in golden hamster infected with amastigote stage of Leishmania donovani MHOM/IN/80/Dd8 assessed as appearance of abnormal behavior at 50 mg/kg/day, ip measured for 5 days | Mesocricetus auratus | 2 | organism-based format | Scientific Literature | ||
2. | ALA3095526 | F | Antileishmanial activity against amastigote stage of Leishmania donovani MHOM/IN/80/Dd8 infected in golden hamster assessed as inhibition of parasite multiplication in splen at 50 mg/kg/day, ip administered for 5 days measured on day 7 by Giemsa staining relative to control | Leishmania donovani | 2 | organism-based format | Scientific Literature | ||
3. | ALA3095527 | F | Selectivity index, ratio of CC50 to African green monkey Vero cells to IC50 for amastigote stage of Leishmania donovani MHOM/IN/80/Dd8 | 19 | cell-based format | Scientific Literature | |||
4. | ALA3095528 | A | Cytotoxicity against African green monkey Vero cells assessed as cell viability after 72 hrs by MTT assay | Chlorocebus sabaeus | 22 | cell-based format | Scientific Literature | ||
5. | ALA3095687 | F | Antileishmanial activity against amastigote stage of Leishmania donovani MHOM/IN/80/Dd8 infected in mouse J-774A.1 cells after 72 hrs by luciferase reporter gene assay | Leishmania donovani | 22 | organism-based format | Scientific Literature |