| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3096526 | B | Selectivity ratio of IC50 for PDE10A (unknown origin) to IC50 for PDE2A (unknown origin) | Homo sapiens | 2 | ALA3091315 | assay format | Scientific Literature | |
| 2. | ALA3096527 | B | Inhibition of PDE10A (unknown origin) using tritium labeled cAMP as substrate after 1 hr by scintillation proximity assay | Homo sapiens | 3 | ALA3091315 | single protein format | Scientific Literature | |
| 3. | ALA3096528 | B | Inhibition of PDE2A (unknown origin) using tritium labeled cAMP as substrate after 1 hr by scintillation proximity assay | Homo sapiens | 3 | ALA3091315 | single protein format | Scientific Literature | |
| 4. | ALA3430102 | B | Inhibition of 6-His-tagged human recombinant PDE2A expressed in Sf9 cells using [3H]cGMP incubated for 40 mins by scintillation proximity assay | Homo sapiens | 14 | ALA3425427 | cell-based format | Scientific Literature | |
| 5. | ALA3430103 | P | Solubility in pH 7.4 buffer | 1 | ALA3425427 | small-molecule physicochemical format | Scientific Literature | ||
| 6. | ALA3430104 | P | Solubility in pH 3.9 buffer with 20% HPbetaCD | 1 | ALA3425427 | small-molecule physicochemical format | Scientific Literature | ||
| 7. | ALA3430105 | P | Dissociation constant, pKa of the compound | 2 | ALA3425427 | small-molecule physicochemical format | Scientific Literature | ||
| 8. | ALA3430106 | B | Inhibition of human PDE1A by scintillation proximity assay | Homo sapiens | 1 | ALA3425427 | single protein format | Scientific Literature | |
| 9. | ALA3430107 | B | Inhibition of human PDE3B by scintillation proximity assay | Homo sapiens | 1 | ALA3425427 | single protein format | Scientific Literature | |
| 10. | ALA3430108 | B | Inhibition of 6-His-tagged human recombinant PDE4D3 expressed in Sf9 cells by scintillation proximity assay | Homo sapiens | 1 | ALA3425427 | cell-based format | Scientific Literature | |
| 11. | ALA3430109 | B | Inhibition of 6-His-tagged human recombinant PDE5A3 expressed in Sf9 cells by scintillation proximity assay | Homo sapiens | 1 | ALA3425427 | cell-based format | Scientific Literature | |
| 12. | ALA3430110 | B | Inhibition of human PDE6AB by scintillation proximity assay | Homo sapiens | 1 | ALA3425427 | protein format | Scientific Literature | |
| 13. | ALA3430111 | B | Inhibition of 6-His-tagged human recombinant PDE7A1 expressed in Sf9 cells by scintillation proximity assay | Homo sapiens | 1 | ALA3425427 | cell-based format | Scientific Literature | |
| 14. | ALA3430112 | B | Inhibition of 6-His-tagged human recombinant PDE9A1 expressed in Sf9 cells by scintillation proximity assay | Homo sapiens | 1 | ALA3425427 | cell-based format | Scientific Literature | |
| 15. | ALA3430113 | B | Inhibition of 6-His-tagged rat recombinant PDE10A expressed in Sf9 cells using [3H]cAMP incubated for 60 mins by scintillation proximity assay | Rattus norvegicus | 11 | ALA3425427 | cell-based format | Scientific Literature | |
| 16. | ALA3430114 | B | Inhibition of full length human PDE11A4 expressed in HEK cells by scintillation proximity assay | Homo sapiens | 1 | ALA3425427 | cell-based format | Scientific Literature | |
| 17. | ALA3430115 | A | Drug metabolism in human liver microsomes at 1 uM incubated for 15 mins at 37 degC | Homo sapiens | 11 | ALA3425427 | assay format | Scientific Literature | |
| 18. | ALA3430116 | A | Drug metabolism in rat liver microsomes at 1 uM incubated for 15 mins at 37 degC | Rattus norvegicus | 11 | ALA3425427 | assay format | Scientific Literature | |
| 19. | ALA3430117 | P | Kinetic solubility in pH 7.4 buffer incubated for 4 hrs | 1 | ALA3425427 | small-molecule physicochemical format | Scientific Literature | ||
| 20. | ALA3430118 | P | Dissociation constant, pKa of the compound at 25 degC by potentiometric titration method | 1 | ALA3425427 | small-molecule physicochemical format | Scientific Literature |
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