# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3102568 | B | Inhibition of PTP1B in mouse C2C12 cells assessed as increase of 2-deoxy-D-1,2-[3H]-glucose at 25 uM after 90 mins by beta-scintillation counting | Mus musculus | 5 | cell-based format | Scientific Literature | ||
2. | ALA3102570 | A | Cytotoxicity against mouse C2C12 cells expressing PTP1B, TC-PTP, LMW-PTP and insulin receptor assessed as cell viability after 2 hrs by MTT assay | Mus musculus | 14 | cell-based format | Scientific Literature | ||
3. | ALA3102574 | B | Partial reversible inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrate assessed as residual activity at 25 times IC50 after 1 hr measured after 400 fold dilution | Homo sapiens | 4 | assay format | Scientific Literature | ||
4. | ALA3102577 | B | Selectivity ratio of IC50 for human recombinant LMW-PTP IF2 to IC50 for human recombinant LMW-PTP IF1 | Homo sapiens | 14 | assay format | Scientific Literature | ||
5. | ALA3102578 | B | Selectivity ratio of IC50 for human recombinant LMW-PTP IF2 to IC50 for human recombinant PTP1B | Homo sapiens | 13 | assay format | Scientific Literature | ||
6. | ALA3102579 | B | Selectivity ratio of IC50 for human recombinant LMW-PTP IF1 to IC50 for human recombinant PTP1B | Homo sapiens | 13 | assay format | Scientific Literature | ||
7. | ALA3102580 | B | Inhibition of TC-PTP (unknown origin) expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrate | Homo sapiens | 14 | assay format | Scientific Literature | ||
8. | ALA3102581 | B | Inhibition of human recombinant LMW-PTP IF2 expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrate | Homo sapiens | 14 | assay format | Scientific Literature | ||
9. | ALA3102582 | B | Inhibition of human recombinant PTP1B expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrate | Homo sapiens | 14 | assay format | Scientific Literature | ||
10. | ALA3102583 | B | Inhibition of human recombinant LMW-PTP IF1 expressed in Escherichia coli TB1 using p-nitrophenylphosphate as substrate | Homo sapiens | 14 | assay format | Scientific Literature |