# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3100725 | F | Antitumor activity against Sprague-Dawley rat mammary tumor cells assessed as increase in apoptotic index at 200 mg/kg, po after 7 days by TUNEL assay relative to control | Rattus norvegicus | 4 | ALA3098106 | organism-based format | Scientific Literature | |
2. | ALA3100726 | F | Antitumor activity against BRDU-labeled Sprague-Dawley rat mammary tumor cells assessed as reduction in proliferation index at 200 mg/kg, po after 7 days relative to control | Rattus norvegicus | 4 | ALA3098106 | organism-based format | Scientific Literature | |
3. | ALA3100727 | T | Toxicity in Sprague-Dawley rat assessed as liver weight measured per 100 g of body weight at 200 mg/kg, po after 7 days (Rvb = 3.3 g) | Rattus norvegicus | 2 | ALA3098106 | organism-based format | Scientific Literature | |
4. | ALA3100728 | T | Toxicity in Sprague-Dawley rat assessed as increase in body weight at 200 mg/kg, po after 7 days relative to control | Rattus norvegicus | 6 | ALA3098106 | organism-based format | Scientific Literature | |
5. | ALA3100729 | F | Inhibition of KLF4-ER-mediated rat RK3E cell transformation after 3 weeks | Rattus norvegicus | 6 | ALA3098106 | cell-based format | Scientific Literature | |
6. | ALA3100731 | B | Agonist activity at human RARalpha expressed in HEK293 cells assessed as transcriptional activation at 10'-6 M after 48 hrs by luciferase reporter gene assay | Homo sapiens | 3 | ALA3098106 | cell-based format | Scientific Literature | |
7. | ALA3100732 | B | Agonist activity at RXRalpha in rat RK3E cells assessed as transcriptional activation by luciferase reporter gene assay | Rattus norvegicus | 6 | ALA3098106 | cell-based format | Scientific Literature | |
8. | ALA3100733 | B | Binding affinity to human RXRalpha ligand binding domain by fluorescence assay | Homo sapiens | 6 | ALA3098106 | single protein format | Scientific Literature | |
9. | ALA3101228 | T | Toxicity in 216 days old Sprague-Dawley rat assessed as increase in serum triglyceride level at 200 mg/kg, po administered with diet after 7 days relative to control | Rattus norvegicus | 3 | ALA3098106 | organism-based format | Scientific Literature |