| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3102109 | B | Selectivity ratio of IC50 for PARP1 (unknown origin) to IC50 for human tankyrase2 | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 2. | ALA3102110 | B | Selectivity ratio of IC50 for PARP1 (unknown origin) to IC50 for human tankyrase1 | Homo sapiens | 6 | assay format | Scientific Literature | ||
| 3. | ALA3102112 | B | Inhibition of human recombinant IMPDH2 by spectrophotometry | Homo sapiens | 13 | single protein format | Scientific Literature | ||
| 4. | ALA3102113 | B | Inhibition of PARP1 (unknown origin) after 1 hr by spectrophotometry | Homo sapiens | 13 | single protein format | Scientific Literature | ||
| 5. | ALA3102114 | B | Inhibition of human tankyrase2 after 2 hrs by spectrophotometry | Homo sapiens | 13 | single protein format | Scientific Literature | ||
| 6. | ALA3102115 | B | Inhibition of human tankyrase1 after 30 mins by spectrophotometry | Homo sapiens | 13 | single protein format | Scientific Literature | ||
| 7. | ALA3829027 | B | Inhibition of human PARP-2 (unknown origin) using histone as substrate incubated for 1 hr by chemiluminescence assay | Homo sapiens | 17 | single protein format | Scientific Literature | ||
| 8. | ALA3829028 | B | Inhibition of N-terminal GST-tagged human TNKS-2 (849 to 1166 residues) expressed in in insect sf21 cells at 1 uM preincubated for 2 hrs followed by substrate addition measured after 30 mins | Homo sapiens | 77 | cell-based format | Scientific Literature | ||
| 9. | ALA3829126 | B | Inhibition of N-terminal GST-tagged human TNKS-2 (849 to 1166 residues) expressed in in insect sf21 cells at 100 nM preincubated for 2 hrs followed by substrate addition measured after 30 mins | Homo sapiens | 77 | cell-based format | Scientific Literature | ||
| 10. | ALA3829127 | B | Inhibition of N-terminal GST-tagged human TNKS-2 (849 to 1166 residues) expressed in in insect sf21 cells at 10 nM preincubated for 2 hrs followed by substrate addition measured after 30 mins | Homo sapiens | 77 | cell-based format | Scientific Literature | ||
| 11. | ALA3829128 | F | Antiproliferative activity against human HT-29 cells at 100 uM by MTS assay | Homo sapiens | 41 | cell-based format | Scientific Literature | ||
| 12. | ALA3829129 | F | Antiproliferative activity against human HT-29 cells at 10 uM by MTS assay | Homo sapiens | 41 | cell-based format | Scientific Literature | ||
| 13. | ALA3829130 | F | Antiproliferative activity against human HT-29 cells at 1 uM by MTS assay | Homo sapiens | 41 | cell-based format | Scientific Literature | ||
| 14. | ALA3829133 | B | Inhibition of tankyrase-mediated Wnt signalling in mouse TLg2 cells assessed as percentage of cells above median GFP fluorescent intensity at 10 uM under N2B27 differentiating condition by flow cytometric analysis (Rvb = 50%) | Mus musculus | 8 | cell-based format | Scientific Literature | ||
| 15. | ALA5227342 | B | Inhibition of human TNKS1 (1030 to 1317 residues) measured after 20 hrs | Homo sapiens | 6 | single protein format | Scientific Literature | ||
| 16. | ALA5227343 | B | Inhibition of human TNKS2 (873 to 1162 residues) measured after 15 hrs in presence of NAD+ by fluorescence assay | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 17. | ALA5227344 | B | Inhibition of human recombinant PARP1 incubated for 30 mins in the presence of NAD | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 18. | ALA5227347 | B | Inhibition of IMPDH2 (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature |
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