# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3101514 | A | Half life in Wistar rat at 10 mg/kg, po | Rattus norvegicus | 2 | ALA3098073 | organism-based format | Scientific Literature | |
2. | ALA3101515 | A | Oral bioavailability in Wistar rat at 10 mg/kg | Rattus norvegicus | 2 | ALA3098073 | organism-based format | Scientific Literature | |
3. | ALA3101516 | A | AUC (0 to infinity) in Wistar rat at 10 mg/kg, po | Rattus norvegicus | 2 | ALA3098073 | organism-based format | Scientific Literature | |
4. | ALA3101517 | A | Apparent oral clearance in Wistar rat at 10 mg/kg, po | Rattus norvegicus | 2 | ALA3098073 | organism-based format | Scientific Literature | |
5. | ALA3102014 | P | Lipophilicity, log D of the compound at pH 7.4 by shake-flask method | 2 | ALA3098073 | small-molecule physicochemical format | Scientific Literature | ||
6. | ALA3102015 | A | Cmax in Wistar rat at 10 mg/kg, po | Rattus norvegicus | 2 | ALA3098073 | organism-based format | Scientific Literature | |
7. | ALA3102016 | A | Protein binding in human plasma | Homo sapiens | 2 | ALA3098073 | cell-free format | Scientific Literature | |
8. | ALA3102017 | P | Dissociation constant, pKa of the compound by potentiometric method | 2 | ALA3098073 | small-molecule physicochemical format | Scientific Literature | ||
9. | ALA3102018 | P | Solubility of the compound at pH 7.4 | 2 | ALA3098073 | small-molecule physicochemical format | Scientific Literature | ||
10. | ALA3102019 | P | Solubility of the compound at pH 1 | 2 | ALA3098073 | small-molecule physicochemical format | Scientific Literature | ||
11. | ALA3102020 | A | Apparent permeability of the compound from basolateral to apical direction in human Caco2 cells | Homo sapiens | 2 | ALA3098073 | cell-based format | Scientific Literature | |
12. | ALA3102021 | A | Apparent permeability of the compound from apical to basolateral direction in human Caco2 cells | Homo sapiens | 2 | ALA3098073 | cell-based format | Scientific Literature | |
13. | ALA3102022 | B | Antagonist activity at CRTh2 in human RBC assessed as inhibition of PGD2-induced eosinophil shape change | Homo sapiens | 2 | ALA3098073 | single protein format | Scientific Literature | |
14. | ALA3102023 | F | Antagonist activity at CRTh2 (unknown origin) expressed in CHO.K1 cells assessed as inhibition of PGD2-induced [35S]-GTPgammaS binding after 2 hrs by liquid scintillation counting in presence of 1% human serum albumin | Homo sapiens | 2 | ALA3098073 | cell-based format | Scientific Literature | |
15. | ALA3102127 | F | Antagonist activity at CRTh2 (unknown origin) expressed in CHO.K1 cells assessed as inhibition of PGD2-induced [35S]-GTPgammaS binding after 2 hrs by liquid scintillation counting | Homo sapiens | 38 | ALA3098073 | cell-based format | Scientific Literature | |
16. | ALA3102129 | B | Antagonist activity at CRTh2 in human whole blood assessed as inhibition of PGD2-induced eosinophil shape change | Homo sapiens | 3 | ALA3098073 | single protein format | Scientific Literature | |
17. | ALA3778970 | B | Displacement of [35S]-GTPgammaS from CRTH2 receptor (unknown origin) expressed in CHOK1 cell membrane after 1 hr by liquid scintillation counter | Homo sapiens | 22 | ALA3774370 | cell-based format | Scientific Literature | |
18. | ALA3778972 | B | Antagonist activity at CRTH2 receptor (unknown origin) expressed in CHOK1 cells assessed as dissociation half life measured up to 25 hrs by GTPgammaS assay | Homo sapiens | 26 | ALA3774370 | cell-based format | Scientific Literature |