| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3101096 | Functional | Ratio of IC50 for human CRL2813 cells after 3 days by SRB assay in presence of HRI-targeting siRNA to IC50 for human CRL2813 cells after 3 days by SRB assay in presence of non-targeting siRNA | Homo sapiens | 2 | ALA3098030 | cell-based format | Scientific Literature | |
| 2. | ALA3101097 | Functional | Antiproliferative activity against human CRL2813 cells after 3 days by SRB assay in presence of HRI-targeting siRNA | Homo sapiens | 6 | ALA3098030 | cell-based format | Scientific Literature | |
| 3. | ALA3101098 | Functional | Antiproliferative activity against human CRL2813 cells after 3 days by SRB assay in presence of non-targeting siRNA | Homo sapiens | 6 | ALA3098030 | cell-based format | Scientific Literature | |
| 4. | ALA3101099 | Binding | Activation of HRI in human CRL-2813-pBISA-DL(ATF-4) reporter cells assessed as concentration required to obtain F-luciferase expression/R-luciferase expression ratio 3 | Homo sapiens | 30 | ALA3098030 | assay format | Scientific Literature | |
| 5. | ALA3101102 | Binding | Activation of HRI in human CRL-2813-pBISA-DL(ATF-4) reporter cells assessed as eIF2alpha phosphorylation after 8 to 32 hrs by dual-luciferase reporter gene assay | Homo sapiens | 4 | ALA3098030 | assay format | Scientific Literature | |
| 6. | ALA3101113 | Functional | Cytotoxicity against human CRL2813 cells after 5 days by SRB assay | Homo sapiens | 48 | ALA3098030 | cell-based format | Scientific Literature | |
| 7. | ALA3101114 | Binding | Activation of HRI in human CRL-2813-pBISA-DL(ATF-4) reporter cells assessed as reduction of ternary complex at 30 uM by dual-luciferase reporter gene assay relative to control | Homo sapiens | 48 | ALA3098030 | assay format | Scientific Literature |
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