# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3105977 | B | Inhibition of rat recombinant 6xHis-tagged DYRK1A catalytic domain (1 to 502) expressed in Escherichia coli BL21 (DE3) using N-terminal fluorescein coupled KISGRLSPIMTEQ as substrate after 30 mins by HPLC analysis in presence of 50 uM ATP | Rattus norvegicus | 25 | assay format | Scientific Literature | ||
2. | ALA4305756 | B | Displacement of tracer 222 from GST-tagged recombinant human AAK1 catalytic domain (1 to 510 amino acids) expressed in insect cells shaken for 30 secs and incubated for 1 hr by LanthaScreen Eu kinase binding assay | Homo sapiens | 29 | cell-based format | Scientific Literature | ||
3. | ALA4305759 | F | Antiviral activity against Dengue virus 2 New Guinea C infected in human HuH7 cells assessed as reduction in viral infection measured at 48 hrs post infection by renilla-luciferase substrate based assay | dengue virus type 2 | 29 | organism-based format | Scientific Literature | ||
4. | ALA4305768 | A | Cytotoxicity against human HuH7 cells infected with DENV2 New Guinea C by microplate alamar blue assay | Homo sapiens | 29 | cell-based format | Scientific Literature |