# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3528990 | ADME | Binding affinity to recombinant human ENT1 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by scintillation counting analysis | Homo sapiens | 3 | ALA3526052 | assay format | Scientific Literature | |
2. | ALA3528991 | ADME | Binding affinity to recombinant human ENT2 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by scintillation counting analysis | Homo sapiens | 3 | ALA3526052 | assay format | Scientific Literature | |
3. | ALA3528992 | ADME | Binding affinity to recombinant human CNT1 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by scintillation counting analysis | Homo sapiens | 3 | ALA3526052 | assay format | Scientific Literature | |
4. | ALA3528993 | ADME | Binding affinity to recombinant human CNT2 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 15 mins by scintillation counting analysis | Homo sapiens | 3 | ALA3526052 | assay format | Scientific Literature | |
5. | ALA3528994 | ADME | Binding affinity to recombinant human CNT3 expressed in Saccharomyces cerevisiae assessed as inhibition of [3H]-uridine transport after 5 mins by scintillation counting analysis | Homo sapiens | 3 | ALA3526052 | assay format | Scientific Literature | |
6. | ALA3529001 | ADME | Drug transport in Xenopus laevis oocytes assessed as recombinant human CNT1-mediated uptake by measuring induction of sodium currents at 100 to 500 uM by electrophysiological method | Homo sapiens | 3 | ALA3526052 | cell-based format | Scientific Literature | |
7. | ALA3529002 | ADME | Drug transport in Xenopus laevis oocytes assessed as recombinant human CNT2-mediated uptake by measuring induction of sodium currents at 100 to 500 uM by electrophysiological method | Homo sapiens | 3 | ALA3526052 | cell-based format | Scientific Literature | |
8. | ALA3529003 | ADME | Drug transport in Xenopus laevis oocytes assessed as recombinant human CNT3-mediated uptake by measuring induction of sodium currents at 100 to 500 uM by electrophysiological method | Homo sapiens | 3 | ALA3526052 | cell-based format | Scientific Literature | |
9. | ALA3590926 | Binding | Inhibition of Neisseria meningitidis alpha-1,4-galactosyltransferase LgtC at 20% donor UDP-Gal turn over rates by inorganic phosphate release from UDP and malachite green dye based inorganic phosphate detection based assay | Neisseria meningitidis | 1 | ALA3588762 | single protein format | Scientific Literature | |
10. | ALA3590927 | Binding | Inhibition of Neisseria meningitidis alpha-1,4-galactosyltransferase LgtC at 50% donor UDP-Gal turn over rates by inorganic phosphate release from UDP and malachite green dye based inorganic phosphate detection based assay | Neisseria meningitidis | 1 | ALA3588762 | single protein format | Scientific Literature | |
11. | ALA3590928 | Binding | Inhibition of Neisseria meningitidis alpha-1,4-galactosyltransferase LgtC at 90% donor UDP-Gal turn over rates by inorganic phosphate release from UDP and malachite green dye based inorganic phosphate detection based assay | Neisseria meningitidis | 1 | ALA3588762 | single protein format | Scientific Literature | |
12. | ALA3591086 | Binding | Inhibition of bovine beta-1,4-GalT LgtC at 10% to 50 donor UDP-Gal turn over rates by inorganic phosphate release from UDP and malachite green dye based inorganic phosphate detection based assay | Bos taurus | 1 | ALA3588762 | single protein format | Scientific Literature | |
13. | ALA875619 | ADME | Cleavage rate was reported | 3 | ALA1128972 | assay format | Scientific Literature | ||
14. | ALA643273 | Physicochemical | Partition coefficient (logP) | 13 | ALA1126075 | small-molecule physicochemical format | Scientific Literature | ||
15. | ALA653965 | Binding | Compound was evaluated for its effect on the activity of mammalian Carbamoyl-phosphate synthetase in the multienzyme polypeptide CAD at a concentration of 1.6mM | 2 | ALA1129083 | single protein format | Scientific Literature | ||
16. | ALA665308 | Binding | Compound was tested for its binding affinity against cytidine deaminase. | 3 | ALA1131016 | single protein format | Scientific Literature | ||
17. | ALA702075 | Functional | In vitro inhibitory activity against growth of L1210 mouse leukemia cells at 10E-4 M concentration; IA means Inactive | Mus musculus | 33 | ALA1122091 | cell-based format | Scientific Literature | |
18. | ALA706055 | Functional | In vivo percent increase in life span (%ILS) of mice bearing L1210 leukemia at a dose of 400 mg/kg | Mus musculus | 33 | ALA1122091 | organism-based format | Scientific Literature | |
19. | ALA708713 | Functional | The concentration required to inhibit the growth of L-1210 leukemic cells was evaluated; 1E-3 to 1E-4 | Mus musculus | 2 | ALA1123079 | cell-based format | Scientific Literature | |
20. | ALA708716 | Functional | The concentration required (hypoxanthine+uridine) to inhibit the growth of L-1210 leukemic cells was evaluated | Mus musculus | 4 | ALA1123079 | cell-based format | Scientific Literature |