| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3107578 | B | Inhibition of recombinant rat alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current by voltage clamp electrophysiology method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 2. | ALA3107579 | B | Inhibition of recombinant rat alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current by voltage clamp electrophysiology method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 3. | ALA3107581 | B | Inhibition of recombinant rat alpha3beta2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current by voltage clamp electrophysiology method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 4. | ALA3107582 | B | Inhibition of recombinant rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-induced current by voltage clamp electrophysiology method | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 5. | ALA4013135 | B | Antagonist activity at rat alpha3beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins at -70 mV holding potential by two electrode voltage clamp method | Rattus norvegicus | 19 | assay format | Scientific Literature | ||
| 6. | ALA4013136 | B | Antagonist activity at rat alpha6/alpha3beta4 nACHR expressed in xenopous laevis oocyte assessed as inhibition of ACh induced channel current after 5 mins at -70 mV holding potential by two electrode voltage clamp method | Rattus norvegicus | 18 | assay format | Scientific Literature | ||
| 7. | ALA4013137 | B | Selectivity ratio of IC50 for rat alpha6/alpha3beta4 nACHR expressed in xenopous laevis oocyte to IC50 for rat alpha3beta4 nACHR expressed in xenopous laevis oocyte | Rattus norvegicus | 13 | assay format | Scientific Literature | ||
| 8. | ALA4358816 | B | Inhibition of rat alpha9alpha10 nAChR | Rattus norvegicus | 3 | protein complex format | Scientific Literature | ||
| 9. | ALA4358817 | B | Inhibition of rat alpha7 nAChR | Rattus norvegicus | 3 | single protein format | Scientific Literature | ||
| 10. | ALA4358818 | B | Inhibition of human alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-evoked currents by two-electrode voltage clamp assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 11. | ALA4358819 | B | Inhibition of human alpha7 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of ACh-evoked currents by two-electrode voltage clamp assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 12. | ALA4365247 | B | Antagonist activity at rat alpha3beta2 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potential by two electrode voltage-clamp assay | Rattus norvegicus | 38 | cell-based format | Scientific Literature | ||
| 13. | ALA4365248 | A | Antagonist activity at rat alpha6alpha3beta2beta3 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potential by two electrode voltage-clamp assay | Rattus norvegicus | 38 | cell-based format | Scientific Literature | ||
| 14. | ALA4365249 | B | Selectivity ratio of IC50 for rat alpha6/alpha3beta2beta3 nAChR expressed in Xenopus laevis oocytes to IC50 for rat alpha3beta2 nACHR expressed in Xenopus laevis oocytes | Rattus norvegicus | 41 | cell-based format | Scientific Literature | ||
| 15. | ALA4365250 | B | Antagonist activity at rat alpha3beta4 nACHR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potential by two electrode voltage-clamp assay | Rattus norvegicus | 5 | cell-based format | Scientific Literature | ||
| 16. | ALA4365269 | B | Antagonist activity at rat alpha9alpha10 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potential by two electrode voltage-clamp assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 17. | ALA4365270 | B | Antagonist activity at rat alpha6beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of Ach-induced response at -70 mV holding potential by two electrode voltage-clamp assay | Rattus norvegicus | 1 | cell-based format | Scientific Literature | ||
| 18. | ALA4811700 | B | Inhibition of rat alpha6/alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response at 10 uM measured after 5 min by two-electrode voltage-clamp method relative to control | Rattus norvegicus | 7 | cell-based format | Scientific Literature | ||
| 19. | ALA4811701 | B | Inhibition of human alpha6/alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response at 10 uM measured after 5 min by two-electrode voltage-clamp method relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 20. | ALA4811702 | B | Inhibition of human alpha6/alpha3beta4 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acetylcholine-induced current response measured after 5 min by two-electrode voltage-clamp method | Homo sapiens | 53 | cell-based format | Scientific Literature |
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