# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3425210 | Binding | Inhibition of LSD1 (unknown origin) | Homo sapiens | 1 | ALA3421542 | single protein format | Scientific Literature | |
2. | ALA3425211 | Binding | Inhibition of human recombinant LSD1 expressed in Escherichia coli using H3-H4 peptide as substrate assessed as H2O2 produced after 15 mins by amplex red assay | Homo sapiens | 5 | ALA3421542 | assay format | Scientific Literature | |
3. | ALA3425212 | Binding | Inhibition of human recombinant MAOA expressed in Pichia pastoris incubated for 15 mins prior to substrate addition measured after 30 mins by luminescence assay | Homo sapiens | 5 | ALA3421542 | assay format | Scientific Literature | |
4. | ALA3425214 | Binding | Inhibition of human recombinant MAOB expressed in Pichia pastoris at 100 uM incubated for 15 mins prior to substrate addition measured after 30 mins by luminescence assay | Homo sapiens | 3 | ALA3421542 | assay format | Scientific Literature | |
5. | ALA3425217 | Functional | Induction of cell differentiation in human NB4 cells assessed as upregulation of CD11B expression | Homo sapiens | 1 | ALA3421542 | cell-based format | Scientific Literature | |
6. | ALA3425218 | Functional | Induction of cell differentiation in mouse acute promyelocytic leukemic cells | Mus musculus | 1 | ALA3421542 | assay format | Scientific Literature | |
7. | ALA3425221 | Functional | Inhibition of colony formation in mouse acute promyelocytic leukemic cell at 0.25 uM after 7 days by colony forming unit assay | Mus musculus | 3 | ALA3421542 | assay format | Scientific Literature | |
8. | ALA3108411 | Binding | Inhibition of human recombinant LSD1 using dimethylated H3K4 peptide as substrate after 1 hr | Homo sapiens | 11 | ALA3102716 | single protein format | Scientific Literature | |
9. | ALA4814398 | Binding | Inhibition of human LSD1/CoREST expressed in Escherichia coli using histone H3 peptide monomethylated at Lys4 as substrate by peroxidase-coupled assay | Homo sapiens | 3 | ALA4813911 | assay format | Scientific Literature | |
10. | ALA4814399 | Binding | Inhibition of recombinant mouse LSD2 expressed in Escherichia coli using histone H3 peptide dimethylated at Lys4 as substrate by peroxidase-coupled assay | Mus musculus | 3 | ALA4813911 | assay format | Scientific Literature | |
11. | ALA4814400 | Binding | Inhibition of recombinant human MAO-A expressed in Pichia pastoris using kynuramine as substrate by peroxidase-coupled method | Homo sapiens | 3 | ALA4813911 | assay format | Scientific Literature |