| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3107513 | B | Inhibition of human recombinant glutathione reductase using glutathione as substrate preincubated for 30 mins by colorimetric assay | Homo sapiens | 19 | single protein format | Scientific Literature | ||
| 2. | ALA3107514 | B | Inhibition of Trypanosoma cruzi trypanothione reductase expressed in Escherichia coli BL21(DE3) assessed as reduction of oxidized trypanothione preincubated for 30 mins measured for 30 mins by spectrophotometric analysis | Trypanosoma cruzi | 19 | assay format | Scientific Literature | ||
| 3. | ALA3107515 | B | Inhibition of Trypanosoma cruzi trypanothione reductase expressed in Escherichia coli BL21(DE3) assessed as reduction of oxidized trypanothione at 100 uM preincubated for 30 mins measured for 30 mins by spectrophotometric analysis relative to DMSO-treated control | Trypanosoma cruzi | 18 | assay format | Scientific Literature | ||
| 4. | ALA3107516 | F | Selectivity index, ratio of CC50 for mouse peritoneal macrophages to IC50 for Leishmania amazonensis IFLA/BR/1967/PH-8 promastigotes | 15 | assay format | Scientific Literature | |||
| 5. | ALA3107517 | A | Cytotoxicity against mouse peritoneal macrophages after 24 hrs by MTT assay | Mus musculus | 15 | cell-based format | Scientific Literature | ||
| 6. | ALA3107518 | F | Antileishmanial activity against Leishmania amazonensis IFLA/BR/1967/PH-8 promastigotes infected in mouse peritoneal macrophages assessed as parasite growth inhibition after 48 hrs by MTT assay | Leishmania amazonensis | 19 | organism-based format | Scientific Literature | ||
| 7. | ALA3107519 | F | Selectivity index, ratio of CC50 for mouse L929 cells to IC50 for Trypanosoma cruzi Tulahuen amastigotes | 7 | cell-based format | Scientific Literature | |||
| 8. | ALA3107520 | A | Cytotoxicity against mouse L929 cells after 96 hrs by Alamar blue assay | Mus musculus | 7 | cell-based format | Scientific Literature | ||
| 9. | ALA3107521 | F | Trypanocidal activity against Trypanosoma cruzi Tulahuen amastigotes infected in mouse L929 cells assessed as parasite growth inhibition after 7 days by beta-galactosidase assay | Trypanosoma cruzi | 19 | organism-based format | Scientific Literature |
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