# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3106557 | Functional | Agonist activity at rat GPR119 assessed as cAMP accumulation | Rattus norvegicus | 1 | ALA3102800 | assay format | Scientific Literature | |
2. | ALA3106558 | Functional | Agonist activity at mouse GPR119 assessed as cAMP accumulation | Mus musculus | 1 | ALA3102800 | assay format | Scientific Literature | |
3. | ALA3106559 | ADME | Plasma protein binding in cynomolgus monkey | Macaca fascicularis | 1 | ALA3102800 | cell-free format | Scientific Literature | |
4. | ALA3106560 | Binding | Binding affinity to BSEP (unknown origin) | Homo sapiens | 1 | ALA3102800 | single protein format | Scientific Literature | |
5. | ALA3106561 | ADME | Plasma protein binding in human | Homo sapiens | 1 | ALA3102800 | cell-free format | Scientific Literature | |
6. | ALA3106562 | ADME | Inhibition of Cytochrome P450 (unknown origin) | Homo sapiens | 1 | ALA3102800 | assay format | Scientific Literature | |
7. | ALA3106563 | Binding | Inhibition of human ERG by patch-clamp assay | Homo sapiens | 1 | ALA3102800 | single protein format | Scientific Literature | |
8. | ALA3106564 | Binding | Activation of human PXR | Homo sapiens | 1 | ALA3102800 | single protein format | Scientific Literature | |
9. | ALA3106565 | ADME | Oral bioavailability in cynomolgus monkey at 2 mg/kg | Macaca fascicularis | 1 | ALA3102800 | organism-based format | Scientific Literature | |
10. | ALA3106566 | ADME | Volume of distribution at steady state in cynomolgus monkey at 0.5 mg/kg, iv | Macaca fascicularis | 1 | ALA3102800 | organism-based format | Scientific Literature | |
11. | ALA3106567 | ADME | Half life in cynomolgus monkey at 0.5 mg/kg, iv | Macaca fascicularis | 1 | ALA3102800 | organism-based format | Scientific Literature | |
12. | ALA3106568 | ADME | Clearance in cynomolgus monkey at 0.5 mg/kg, iv | Macaca fascicularis | 1 | ALA3102800 | organism-based format | Scientific Literature | |
13. | ALA3106569 | ADME | Oral bioavailability in rat at 2 mg/kg | Rattus norvegicus | 1 | ALA3102800 | organism-based format | Scientific Literature | |
14. | ALA3106570 | ADME | Volume of distribution at steady state in rat at 0.5 mg/kg, iv | Rattus norvegicus | 1 | ALA3102800 | organism-based format | Scientific Literature | |
15. | ALA3106571 | ADME | Half life in rat at 0.5 mg/kg, iv | Rattus norvegicus | 1 | ALA3102800 | organism-based format | Scientific Literature | |
16. | ALA3106572 | ADME | Clearance in rat at 0.5 mg/kg, iv | Rattus norvegicus | 1 | ALA3102800 | organism-based format | Scientific Literature | |
17. | ALA3107123 | ADME | Metabolic stability in human liver microsomes assessed as compound remaining at 1 uM after 30 mins | Homo sapiens | 1 | ALA3102800 | assay format | Scientific Literature | |
18. | ALA3107124 | ADME | Intrinsic clearance in human liver microsomes at 1 uM after 30 mins | Homo sapiens | 1 | ALA3102800 | assay format | Scientific Literature | |
19. | ALA3107222 | Functional | Agonist activity at cynomolgus monkey GPR119 assessed as cAMP accumulation relative to control | Macaca fascicularis | 1 | ALA3102800 | assay format | Scientific Literature | |
20. | ALA3107223 | Functional | Agonist activity at cynomolgus monkey GPR119 assessed as cAMP accumulation | Macaca fascicularis | 1 | ALA3102800 | assay format | Scientific Literature |