# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3106557 | F | Agonist activity at rat GPR119 assessed as cAMP accumulation | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
2. | ALA3106558 | F | Agonist activity at mouse GPR119 assessed as cAMP accumulation | Mus musculus | 1 | assay format | Scientific Literature | ||
3. | ALA3106559 | A | Plasma protein binding in cynomolgus monkey | Macaca fascicularis | 1 | cell-free format | Scientific Literature | ||
4. | ALA3106560 | B | Binding affinity to BSEP (unknown origin) | Homo sapiens | 1 | single protein format | Scientific Literature | ||
5. | ALA3106561 | A | Plasma protein binding in human | Homo sapiens | 1 | cell-free format | Scientific Literature | ||
6. | ALA3106562 | A | Inhibition of Cytochrome P450 (unknown origin) | Homo sapiens | 1 | assay format | Scientific Literature | ||
7. | ALA3106563 | B | Inhibition of human ERG by patch-clamp assay | Homo sapiens | 1 | single protein format | Scientific Literature | ||
8. | ALA3106564 | B | Activation of human PXR | Homo sapiens | 1 | single protein format | Scientific Literature | ||
9. | ALA3106565 | A | Oral bioavailability in cynomolgus monkey at 2 mg/kg | Macaca fascicularis | 1 | organism-based format | Scientific Literature | ||
10. | ALA3106566 | A | Volume of distribution at steady state in cynomolgus monkey at 0.5 mg/kg, iv | Macaca fascicularis | 1 | organism-based format | Scientific Literature | ||
11. | ALA3106567 | A | Half life in cynomolgus monkey at 0.5 mg/kg, iv | Macaca fascicularis | 1 | organism-based format | Scientific Literature | ||
12. | ALA3106568 | A | Clearance in cynomolgus monkey at 0.5 mg/kg, iv | Macaca fascicularis | 1 | organism-based format | Scientific Literature | ||
13. | ALA3106569 | A | Oral bioavailability in rat at 2 mg/kg | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
14. | ALA3106570 | A | Volume of distribution at steady state in rat at 0.5 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
15. | ALA3106571 | A | Half life in rat at 0.5 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
16. | ALA3106572 | A | Clearance in rat at 0.5 mg/kg, iv | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
17. | ALA3107123 | A | Metabolic stability in human liver microsomes assessed as compound remaining at 1 uM after 30 mins | Homo sapiens | 1 | assay format | Scientific Literature | ||
18. | ALA3107124 | A | Intrinsic clearance in human liver microsomes at 1 uM after 30 mins | Homo sapiens | 1 | assay format | Scientific Literature | ||
19. | ALA3107222 | F | Agonist activity at cynomolgus monkey GPR119 assessed as cAMP accumulation relative to control | Macaca fascicularis | 1 | assay format | Scientific Literature | ||
20. | ALA3107223 | F | Agonist activity at cynomolgus monkey GPR119 assessed as cAMP accumulation | Macaca fascicularis | 1 | assay format | Scientific Literature |