# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3107240 | B | Activation of PKCdelta (unknown origin) after 40 mins | Homo sapiens | 32 | single protein format | Scientific Literature | ||
2. | ALA3107241 | F | Induction of necrosis in human HeLa cells assessed as remaining metabolic activity after 30 mins by resazurin dye-based assay | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
3. | ALA3107242 | F | Induction of proimflammatory activity in human primary epidermal keratinocytes assessed as IL-8 release after 6 hrs relative to ingenol 3-angelate | Homo sapiens | 31 | cell-based format | Scientific Literature | ||
4. | ALA3107243 | F | Induction of proimflammatory activity in human primary epidermal keratinocytes assessed as IL-8 release after 6 hrs | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
5. | ALA3107244 | F | Induction of proimflammatory activity in human primary epidermal keratinocytes assessed as TNFalpha release after 6 hrs relative to ingenol 3-angelate | Homo sapiens | 30 | cell-based format | Scientific Literature | ||
6. | ALA3107245 | F | Induction of proimflammatory activity in human primary epidermal keratinocytes assessed as TNFalpha release after 6 hrs | Homo sapiens | 32 | cell-based format | Scientific Literature | ||
7. | ALA3107246 | F | Immunostimulatory activity in polymorphonuclear leukocytes (unknown origin) assessed as induction of oxidative burst after 40 mins by fluorescence assay relative to ingenol 3-angelate | Not specified | 30 | cell-based format | Scientific Literature | ||
8. | ALA3107247 | F | Immunostimulatory activity in polymorphonuclear leukocytes (unknown origin) assessed as induction of oxidative burst after 40 mins by fluorescence assay | Not specified | 32 | cell-based format | Scientific Literature | ||
9. | ALA3107248 | P | Chemical stability of the compound in aqueous buffer with less than 30% organic solvent assessed as compound recovery at pH 7.4 measured over 16 hrs by HPLC analysis | 32 | small-molecule physicochemical format | Scientific Literature | |||
10. | ALA4273378 | F | Antiviral activity against Human immunodeficiency virus 1 NL4-3 infected in human MT4 cells measured on day 3 post infection by Nano-Glo luciferase reporter gene assay | Human immunodeficiency virus 1 | 22 | organism-based format | Scientific Literature | ||
11. | ALA4273379 | A | Cytotoxicity against human MT4 cells after 3 days by CytoTox-Glo assay | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
12. | ALA4273380 | T | Selectivity index, ratio of CC50 for human MT4 cells to EC50 for Human immunodeficiency virus 1 NL4-3 infected in human MT4 cells | 22 | cell-based format | Scientific Literature | |||
13. | ALA4273381 | F | Potency index, ratio AZT EC50 to test compound EC50 for Human immunodeficiency virus 1 NL4-3 infected in human MT4 cells | Human immunodeficiency virus 1 | 1 | organism-based format | Scientific Literature | ||
14. | ALA4273382 | F | Reactivation of latent HIV1 infected in human U1 cells assessed as increase in p24 production after 72 hrs by ELISA | Human immunodeficiency virus 1 | 2 | organism-based format | Scientific Literature | ||
15. | ALA4273383 | A | Cytotoxicity against human U937 cells after 3 days by CytoTox-Glo assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
16. | ALA4273384 | F | Reactivation of latent HIV1 infected in human J-Lat A2 cells assessed as increase in GFP expression at 10 to 50 nM after 72 hrs by flow cytometric method | Human immunodeficiency virus 1 | 2 | organism-based format | Scientific Literature |