| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3108020 | Binding | Inhibition of pRb p110 phosphorylation in human HCT116 cells after 48 hrs by Western blotting | Homo sapiens | 1 | ALA3102801 | cell-based format | Scientific Literature | |
| 2. | ALA3107984 | Binding | Inhibition of pRb p110 phosphorylation in human MDA-MB-231 cells after 48 hrs by Western blotting | Homo sapiens | 1 | ALA3102801 | cell-based format | Scientific Literature | |
| 3. | ALA3107985 | Binding | Inhibition of pRb p110 phosphorylation in human HCT116 cells at 5 to 10 uM after 48 hrs by Western blotting relative to unphosphorylated p105 | Homo sapiens | 1 | ALA3102801 | cell-based format | Scientific Literature | |
| 4. | ALA3107986 | Binding | Inhibition of pRb p110 phosphorylation in human MDA-MB-231 cells at 5 to 10 uM after 48 hrs by Western blotting relative to unphosphorylated p105 | Homo sapiens | 1 | ALA3102801 | cell-based format | Scientific Literature | |
| 5. | ALA3107987 | Functional | Cell cycle arrest in human HCT116 cells assessed as accumulation of G2-M phase at 10 uM after 48 hrs using propidium iodide staining by flow cytometric analysis (Rvb = 19.2%) | Homo sapiens | 1 | ALA3102801 | cell-based format | Scientific Literature | |
| 6. | ALA3107988 | Functional | Cell cycle arrest in human HCT116 cells assessed as accumulation of G0-G1 phase at 10 uM after 48 hrs using propidium iodide staining by flow cytometric analysis (Rvb = 45.7%) | Homo sapiens | 1 | ALA3102801 | cell-based format | Scientific Literature | |
| 7. | ALA3107989 | Functional | Cell cycle arrest in human HCT116 cells assessed as accumulation of sub-G0-G1 phase at 10 uM after 48 hrs using propidium iodide staining by flow cytometric analysis (Rvb = 15.2%) | Homo sapiens | 1 | ALA3102801 | cell-based format | Scientific Literature | |
| 8. | ALA3107990 | Functional | Cell cycle arrest in human HCT116 cells assessed as accumulation of G2-M phase at 5 uM after 48 hrs using propidium iodide staining by flow cytometric analysis (Rvb = 19.2%) | Homo sapiens | 1 | ALA3102801 | cell-based format | Scientific Literature | |
| 9. | ALA3107991 | Functional | Cell cycle arrest in human HCT116 cells assessed as accumulation of G0-G1 phase at 5 uM after 48 hrs using propidium iodide staining by flow cytometric analysis (Rvb = 45.7%) | Homo sapiens | 1 | ALA3102801 | cell-based format | Scientific Literature | |
| 10. | ALA3107992 | Functional | Cell cycle arrest in human HCT116 cells assessed as accumulation of sub-G0-G1 phase at 5 uM after 48 hrs using propidium iodide staining by flow cytometric analysis (Rvb = 15.2%) | Homo sapiens | 1 | ALA3102801 | cell-based format | Scientific Literature | |
| 11. | ALA3107993 | Functional | Cell cycle arrest in human MDA-MB-231 cells assessed as accumulation of G2-M phase at 10 uM after 48 hrs using propidium iodide staining by flow cytometric analysis (Rvb = 27.5%) | Homo sapiens | 1 | ALA3102801 | cell-based format | Scientific Literature | |
| 12. | ALA3107994 | Functional | Cell cycle arrest in human MDA-MB-231 cells assessed as accumulation of G0-G1 phase at 10 uM after 48 hrs using propidium iodide staining by flow cytometric analysis (Rvb = 42.2%) | Homo sapiens | 1 | ALA3102801 | cell-based format | Scientific Literature | |
| 13. | ALA3107995 | Functional | Cell cycle arrest in human MDA-MB-231 cells assessed as accumulation of sub-G0-G1 phase at 10 uM after 48 hrs using propidium iodide staining by flow cytometric analysis (Rvb = 8.4%) | Homo sapiens | 1 | ALA3102801 | cell-based format | Scientific Literature | |
| 14. | ALA3107996 | Functional | Cell cycle arrest in human MDA-MB-231 cells assessed as accumulation of G2-M phase at 5 uM after 48 hrs using propidium iodide staining by flow cytometric analysis (Rvb = 27.5%) | Homo sapiens | 1 | ALA3102801 | cell-based format | Scientific Literature | |
| 15. | ALA3107997 | Functional | Cell cycle arrest in human MDA-MB-231 cells assessed as accumulation of G0-G1 phase at 5 uM after 48 hrs using propidium iodide staining by flow cytometric analysis (Rvb = 42.2%) | Homo sapiens | 1 | ALA3102801 | cell-based format | Scientific Literature | |
| 16. | ALA3107998 | Functional | Cell cycle arrest in human MDA-MB-231 cells assessed as accumulation of sub-G0-G1 phase at 5 uM after 48 hrs using propidium iodide staining by flow cytometric analysis (Rvb = 8.4%) | Homo sapiens | 1 | ALA3102801 | cell-based format | Scientific Literature | |
| 17. | ALA3107999 | ADME | Therapeutic index, ratio of IC50 for human HeDe cells to IC50 for human HCT116 cells | Homo sapiens | 1 | ALA3102801 | cell-based format | Scientific Literature | |
| 18. | ALA3108000 | ADME | Therapeutic index, ratio of IC50 for human HeDe cells to IC50 for human MDA-MB-231 cells | Homo sapiens | 1 | ALA3102801 | cell-based format | Scientific Literature | |
| 19. | ALA3108001 | ADME | Cytotoxicity against human HuDe cells after 48 hrs by sulforhodamine B assay | Homo sapiens | 1 | ALA3102801 | cell-based format | Scientific Literature | |
| 20. | ALA3108002 | Functional | Growth inhibition of human MDA-MB-468 cells after 48 hrs by sulforhodamine B assay | Homo sapiens | 4 | ALA3102801 | cell-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!