| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3106085 | B | Inhibition of RORgammat receptor ligand binding domain in mouse spleen CD4+ T cells assessed as inhibition of IL-17 production after 3 days by ELISA | Mus musculus | 20 | cell-based format | Scientific Literature | ||
| 2. | ALA3106086 | B | Inhibition of N-(2-chloro-6-fluorobenzyl)-N-((2'-methoxy-[1,1'-biphenyl]-4-yl)methyl)benzenesulfonamide-induced APC-labeled RORgammat receptor ligand binding domain (unknown origin) after 1 hr by FRET assay | Homo sapiens | 46 | single protein format | Scientific Literature | ||
| 3. | ALA3106087 | B | Inhibition of APC-labeled RORgammat receptor ligand binding domain (unknown origin) after 1 hr by FRET assay | Homo sapiens | 52 | single protein format | Scientific Literature | ||
| 4. | ALA3385303 | B | Inverse agonist activity at RORgammaT (unknown origin) by Jurkat cell based luciferase assay | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA3385304 | B | Inverse agonist activity at human recombinant N-terminally 6xHis-tagged RORgamma ligand binding domain (unknown origin) expressed in Escherichia coli incubated for 1 hr by FRET assay | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 6. | ALA3385306 | B | Inverse agonist activity at recombinant N-terminally 6xHis-tagged RORgamma ligand binding domain (unknown origin) expressed in Escherichia coli incubated for 1 hr by FRET assay relative to control | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 7. | ALA3385307 | B | Inverse agonist activity at recombinant N-terminally GST-tagged RORbeta ligand binding domain (unknown origin) expressed in Escherichia coli incubated for 1 hr by FRET assay | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 8. | ALA3385308 | B | Inverse agonist activity at recombinant N-terminally GST-tagged RORbeta ligand binding domain (unknown origin) expressed in Escherichia coli incubated for 1 hr by FRET assay relative to control | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 9. | ALA3385309 | B | Inverse agonist activity at RORgammaT (unknown origin) by M1H assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 10. | ALA3385310 | B | Inverse agonist activity at RORgammaT (unknown origin) by M1H assay relative to control | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 11. | ALA3385311 | B | Inverse agonist activity at RORalpha (unknown origin) by M1H assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 12. | ALA3385312 | B | Inverse agonist activity at RORbeta (unknown origin) by M1H assay | Homo sapiens | 4 | single protein format | Scientific Literature | ||
| 13. | ALA3369183 | B | Activity at human RoRc in human Jurkat cells assessed as inhibition of IL-17 promoter | Homo sapiens | 8 | cell-based format | Scientific Literature | ||
| 14. | ALA4144984 | B | Inverse agonist activity at APC-labeled RORgammat LBD (unknown origin) assessed as inhibition of N-(2-chloro-6-fluorobenzyl)-N-((2'-methoxy-[1,1'-biphenyl]-4-yl)methyl)benzenesulfonamide-induced co-activator SRC1 peptide recruitment after 1 hr by FRET based LANCE assay | Homo sapiens | 14 | single protein format | Scientific Literature | ||
| 15. | ALA4144985 | B | Inverse agonist activity at APC-labeled RORgammat LBD (unknown origin) assessed as inhibition of N-(2-chloro-6-fluorobenzyl)-N-((2'-methoxy-[1,1'-biphenyl]-4-yl)methyl)benzenesulfonamide-induced co-activator SRC1 peptide recruitment after 1 hr by FRET based LANCE assay relative to control | Homo sapiens | 10 | single protein format | Scientific Literature | ||
| 16. | ALA4144986 | B | Inverse agonist activity at biotinylated RORgammat LBD (unknown origin) assessed as inhibition of N-(2-chloro-6-fluorobenzyl)-N-((2'-methoxy-[1,1'-biphenyl]-4-yl)methyl)benzenesulfonamide-induced co-activator SRC1 peptide recruitment after 1 hr by dual FRET based LANCE assay | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 17. | ALA4144987 | B | Inverse agonist activity at biotinylated RORgammat LBD (unknown origin) assessed as inhibition of N-(2-chloro-6-fluorobenzyl)-N-((2'-methoxy-[1,1'-biphenyl]-4-yl)methyl)benzenesulfonamide-induced co-activator SRC1 peptide recruitment after 1 hr by dual FRET based LANCE assay relative to control | Homo sapiens | 8 | single protein format | Scientific Literature |
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