# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3112088 | Functional | Cytotoxicity against human SK-MEL-2 cells assessed as time required for rapid onset of action at 1 uM treated up to 4 hrs followed by compound-washout by CellTiter-Glo assay | Homo sapiens | 8 | ALA3108677 | cell-based format | Scientific Literature | |
2. | ALA3112089 | Functional | Cytotoxicity against human HeLa cells assessed as time required for rapid onset of action at 1 uM treated up to 4 hrs followed by compound-washout by CellTiter-Glo assay | Homo sapiens | 8 | ALA3108677 | cell-based format | Scientific Literature | |
3. | ALA3112090 | ADME | Metabolic stability in mouse plasma at 10 uM by HPLC analysis | Mus musculus | 8 | ALA3108677 | cell-free format | Scientific Literature | |
4. | ALA3112091 | Physicochemical | Solubility of the compound in PBS after 18 hrs by HPLC analysis | 8 | ALA3108677 | small-molecule physicochemical format | Scientific Literature | ||
5. | ALA3112093 | Binding | Induction of MDM2 pre-mRNA alternative-splicing in human Rh18 cells assessed as time required for major splicing changes at 1 uM by RT-PCR analysis | Homo sapiens | 8 | ALA3108677 | cell-based format | Scientific Literature | |
6. | ALA3112094 | Functional | Cytotoxicity against human JeKo1 cells after 72 hrs by CellTiter-Glo assay | Homo sapiens | 20 | ALA3108677 | cell-based format | Scientific Literature |