# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3110853 | F | Anesthetic effect on prelimb-bud stage Xenopus laevis tadpole assessed as loss of swimming reflex at 10 uM after 3 hrs | Xenopus laevis | 3 | ALA3108741 | organism-based format | Scientific Literature | |
2. | ALA3110856 | F | Anesthetic effect on prelimb-bud stage Xenopus laevis tadpole assessed as loss of righting reflex after 3 hrs | Xenopus laevis | 12 | ALA3108741 | organism-based format | Scientific Literature | |
3. | ALA3110857 | B | Positive allosteric modulation of wild type rat alpha1beta2gamma2L GABAA receptor expressed in HEK293 cells assessed as longest-lived intracluster closed time at 20 uM by by two-electrode voltage clamp technique relative to control | Rattus norvegicus | 5 | ALA3108741 | cell-based format | Scientific Literature | |
4. | ALA3110858 | B | Positive allosteric modulation of wild type rat alpha1beta2gamma2L GABAA receptor expressed in HEK293 cells assessed as longest-lived intracluster open time at 20 uM by by two-electrode voltage clamp technique relative to control | Rattus norvegicus | 5 | ALA3108741 | cell-based format | Scientific Literature | |
5. | ALA3110859 | B | Positive allosteric modulation of wild type rat alpha1beta2gamma2L GABAA receptor expressed in HEK293 cells assessed as OT long at 20 uM by by two-electrode voltage clamp technique | Rattus norvegicus | 5 | ALA3108741 | cell-based format | Scientific Literature | |
6. | ALA3110864 | B | Positive allosteric modulation of rat alpha1beta2gamma2L GABAA receptor expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced chloride current elicitation by two-electrode voltage clamp technique relative to control | Rattus norvegicus | 14 | ALA3108741 | cell-based format | Scientific Literature | |
7. | ALA3110865 | B | Positive allosteric modulation of rat alpha1beta2gamma2L GABAA receptor expressed in Xenopus laevis oocytes assessed as chloride current elicitation at 10 uM by two-electrode voltage clamp technique relative to GABA | Rattus norvegicus | 14 | ALA3108741 | cell-based format | Scientific Literature | |
8. | ALA3110866 | B | Positive allosteric modulation of rat alpha1beta2gamma2L GABAA receptor expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced chloride current elicitation at 10 uM by two-electrode voltage clamp technique relative to control | Rattus norvegicus | 14 | ALA3108741 | cell-based format | Scientific Literature | |
9. | ALA3110867 | B | Positive allosteric modulation of rat alpha1beta2gamma2L GABAA receptor expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced chloride current elicitation at 1 uM by two-electrode voltage clamp technique relative to control | Rattus norvegicus | 14 | ALA3108741 | cell-based format | Scientific Literature | |
10. | ALA3110868 | B | Positive allosteric modulation of rat alpha1beta2gamma2L GABAA receptor expressed in Xenopus laevis oocytes assessed as potentiation of GABA-induced chloride current elicitation at 0.1 uM by two-electrode voltage clamp technique relative to control | Rattus norvegicus | 14 | ALA3108741 | cell-based format | Scientific Literature | |
11. | ALA3110870 | B | Displacement of [35S]TBPS from rat picrotoxin binding site of GABAA receptor after 2 hrs by scintillation counting analysis | Rattus norvegicus | 14 | ALA3108741 | assay format | Scientific Literature |