# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3110555 | B | Selectivity ratio of IC50 for human SGLT1 to IC50 for human SGLT2 | Homo sapiens | 3 | ALA3108724 | assay format | Scientific Literature | |
2. | ALA3110611 | B | Inhibition of GLUT1-mediated [3H]2-deoxy-D-glucose uptake in rat L6 cells at 10 uM preincubated for 5 mins followed by 3H]2-deoxy-D-glucose addition measured after 15 mins by liquid scintillation counting analysis | Rattus norvegicus | 3 | ALA3108724 | cell-based format | Scientific Literature | |
3. | ALA3110613 | B | Inhibition of human SGLT1-mediated [14C]-AMG uptake expressed in CHOK cells preincubated for 10 mins followed by [14C]-AMG addition measured after 120 mins by liquid scintillation counting analysis | Homo sapiens | 3 | ALA3108724 | cell-based format | Scientific Literature | |
4. | ALA3110614 | F | Induction of urinary glucose excretion in Sprague-Dawley rat at 30 mg/kg, po measured per 200 g body weight per day after 24 hrs | Rattus norvegicus | 11 | ALA3108724 | organism-based format | Scientific Literature | |
5. | ALA3110615 | B | Inhibition of human SGLT2-mediated [14C]-AMG uptake expressed in CHOK cells preincubated for 10 mins followed by [14C]-AMG addition measured after 120 mins by liquid scintillation counting analysis | Homo sapiens | 11 | ALA3108724 | cell-based format | Scientific Literature |