# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3111658 | A | Cytotoxicity against human BEAS2B cells up to 10 uM after 72 hrs by MTS assay | Homo sapiens | 1 | ALA3108719 | cell-based format | Scientific Literature | |
2. | ALA3111659 | B | Inhibition of IL13-stimulated SH2 domain of STAT6 phosphorylation at Tyr641 in human BEAS2B cells at 1 to 10 uM incubated for 2 hrs prior to IL-13 challenge measured after 1 hr by Western blotting analysis | Homo sapiens | 1 | ALA3108719 | cell-based format | Scientific Literature | |
3. | ALA3111660 | B | Inhibition of IL4-stimulated SH2 domain of STAT6 phosphorylation at Tyr641 in human BEAS2B cells at 1 to 10 uM incubated for 2 hrs prior to IL-4 challenge measured after 1 hr by Western blotting analysis | Homo sapiens | 1 | ALA3108719 | cell-based format | Scientific Literature | |
4. | ALA3110544 | B | Inhibition of IL4-stimulated SH2 domain of STAT6 phosphorylation at Tyr641 in human BEAS2B cells at 1 to 10 uM incubated for 2 to 48 hrs prior to IL-4 challenge measured after 1 hr by Western blotting analysis | Homo sapiens | 1 | ALA3108719 | cell-based format | Scientific Literature | |
5. | ALA3743446 | A | Cytotoxicity against human MDA-MB-468 cells assessed as cell proliferation after 72 hrs by MTS assay | Homo sapiens | 6 | ALA3739303 | cell-based format | Scientific Literature | |
6. | ALA3743447 | B | Inhibition of IL6-induced STAT1 phosphorylation at Y701 in CD4+ T lymphocytes isolated from C57BL/6J mouse preincubated for 2 hrs followed by activation with plate-bound anti-CD3/anti-CD28 and IL6 for 15 mins by Western blot analysis | Mus musculus | 6 | ALA3739303 | cell-based format | Scientific Literature | |
7. | ALA3743448 | B | Inhibition of IL6-induced STAT3 phosphorylation at Y705 in CD4+ T lymphocytes isolated from C57BL/6J mouse preincubated for 2 hrs followed by activation with plate-bound anti-CD3/anti-CD28 for 15 mins by Western blot analysis | Mus musculus | 6 | ALA3739303 | cell-based format | Scientific Literature | |
8. | ALA3743647 | B | Inhibition of IL4-induced STAT6 phosphorylation at Y641 in CD4+ T lymphocytes isolated from C57BL/6J mouse preincubated for 2 hrs followed by activation with plate-bound anti-CD3/anti-CD28 and IL4 for 15 mins by Western blot analysis | Mus musculus | 6 | ALA3739303 | cell-based format | Scientific Literature | |
9. | ALA3743648 | B | Inhibition of IL3-stimulated STAT6 SH2 domain phosphorylation in human Beas-2B cells assessed as inhibition of CCL26 mRNA expression preincubated for 2 hrs followed by stimulation with IL3 for 24 hrs by RT-PCR analysis | Homo sapiens | 2 | ALA3739303 | cell-based format | Scientific Literature | |
10. | ALA3743649 | B | Inhibition of IL3-stimulated STAT6 SH2 domain phosphorylation in human Beas-2B cells assessed as inhibition of CCL26 mRNA expression at 100 nM preincubated for 2 hrs followed by stimulation with IL3 for 24 hrs by RT-PCR analysis relative to control | Homo sapiens | 2 | ALA3739303 | cell-based format | Scientific Literature |