| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3111675 | A | Oral bioavailability in rat at 10 mg/kg | Rattus norvegicus | 3 | ALA3108676 | organism-based format | Scientific Literature | |
| 2. | ALA3111677 | A | Cmax in rat at 10 mg/kg, po | Rattus norvegicus | 3 | ALA3108676 | organism-based format | Scientific Literature | |
| 3. | ALA3111678 | A | AUC in rat at 10 mg/kg, po | Rattus norvegicus | 3 | ALA3108676 | organism-based format | Scientific Literature | |
| 4. | ALA3111679 | A | Hepatic extraction ratio in rat at 1 mg/kg, iv | Rattus norvegicus | 3 | ALA3108676 | organism-based format | Scientific Literature | |
| 5. | ALA3111680 | P | Dissociation constant, pKa of the compound | 3 | ALA3108676 | small-molecule physicochemical format | Scientific Literature | ||
| 6. | ALA3111681 | A | Apparent permeability across apical to basolateral side in pig LLC-PK1 cells expressing MDR1 assessed as compound recovery | Sus scrofa | 3 | ALA3108676 | cell-based format | Scientific Literature | |
| 7. | ALA3111682 | A | Efflux ratio of apparent permeability across apical to basolateral side over basolateral to apical side in pig LLC-PK1 cells expressing MDR1 | Sus scrofa | 3 | ALA3108676 | cell-based format | Scientific Literature | |
| 8. | ALA3111683 | A | Apparent permeability across apical to basolateral side in pig LLC-PK1 cells | Sus scrofa | 3 | ALA3108676 | cell-based format | Scientific Literature | |
| 9. | ALA3111684 | P | Solubility of the compound | 1 | ALA3108676 | small-molecule physicochemical format | Scientific Literature | ||
| 10. | ALA3111687 | A | Extraction ratio in human liver microsomes | Homo sapiens | 4 | ALA3108676 | assay format | Scientific Literature | |
| 11. | ALA3111688 | A | Extraction ratio in cynomolgus monkey liver microsomes | Macaca fascicularis | 4 | ALA3108676 | microsome format | Scientific Literature | |
| 12. | ALA3111689 | A | Extraction ratio in rat liver microsomes | Rattus norvegicus | 4 | ALA3108676 | assay format | Scientific Literature | |
| 13. | ALA3111690 | A | Extraction ratio in mouse liver microsomes | Mus musculus | 4 | ALA3108676 | microsome format | Scientific Literature | |
| 14. | ALA3111691 | B | Selectivity ratio of IC50 for cKIT (unknown origin) to IC50 for PDGFRbeta in mouse NIH3T3 cells | 1 | ALA3108676 | cell-based format | Scientific Literature | ||
| 15. | ALA3111692 | B | Selectivity ratio of IC50 for cFMS (unknown origin) to IC50 for PDGFRbeta in mouse NIH3T3 cells | 2 | ALA3108676 | cell-based format | Scientific Literature | ||
| 16. | ALA3111693 | B | Selectivity ratio of IC50 for KDR (unknown origin) to IC50 for PDGFRbeta in mouse NIH3T3 cells | 9 | ALA3108676 | cell-based format | Scientific Literature | ||
| 17. | ALA3111695 | A | Inhibition of CYP3A4 (unknown origin) | Homo sapiens | 4 | ALA3108676 | single protein format | Scientific Literature | |
| 18. | ALA3111696 | A | Inhibition of CYP2D6 (unknown origin) | Homo sapiens | 4 | ALA3108676 | single protein format | Scientific Literature | |
| 19. | ALA3111697 | A | Inhibition of CYP2C19 (unknown origin) | Homo sapiens | 4 | ALA3108676 | single protein format | Scientific Literature | |
| 20. | ALA3111860 | B | Inhibition of PDGF-induced PDGFRbeta phosphorylation in mouse NIH3T3 cells incubated for 1 hr prior to PDGF induction measured after 15 mins by fluorescence assay in presence of 50% human plasma | Mus musculus | 6 | ALA3108676 | cell-based format | Scientific Literature |
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