| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA681824 | F | Inhibitory activity, for stimulation of TNF-alpha release in gamma-delta T cells, using a constrained maximum TNF-alpha release of 2700 pg/mL | Homo sapiens | 61 | cell-based format | Scientific Literature | ||
| 2. | ALA681826 | F | pIC50 value for stimulation of TNF-alpha release in gamma-delta T cells, using a constrained maximum TNF-alpha release of 2700 pg/mL | Homo sapiens | 61 | cell-based format | Scientific Literature | ||
| 3. | ALA786021 | F | Bone resorption activity in rats. | Rattus norvegicus | 35 | organism-based format | Scientific Literature | ||
| 4. | ALA924793 | B | Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 | Homo sapiens | 27 | assay format | Scientific Literature | ||
| 5. | ALA924794 | B | Inhibition of human recombinant FPPS expressed in Escherichia coli BL21 after 10 mins | Homo sapiens | 27 | assay format | Scientific Literature | ||
| 6. | ALA924795 | F | Inhibition of bone resorption in rat assessed as phosphate | Rattus norvegicus | 23 | organism-based format | Scientific Literature | ||
| 7. | ALA902036 | F | Bone mineral affinity on hydroxyaptite assessed as retention time by chromatography | 10 | assay format | Scientific Literature | |||
| 8. | ALA902037 | B | Inhibition of human cloned FPPS expressed in Escherichia col BL2 (DE3) | Homo sapiens | 9 | assay format | Scientific Literature | ||
| 9. | ALA902038 | A | Reduction of viability of mouse J744 cells after 48 hrs | Mus musculus | 10 | cell-based format | Scientific Literature | ||
| 10. | ALA902039 | B | Inhibition of RGGT mediated Rap1A prenylation in J744 cells | Mus musculus | 5 | cell-based format | Scientific Literature | ||
| 11. | ALA1028089 | B | Inhibition of human recombinant geranylgeranyl diphosphate synthase | Homo sapiens | 59 | single protein format | Scientific Literature | ||
| 12. | ALA3065755 | B | Inhibition of Aquifex aeolicus IspH expressed in Escherichia coli BL21 (DE3) using HMBPP substrate | Aquifex aeolicus | 21 | assay format | Scientific Literature | ||
| 13. | ALA3369319 | B | Allosteric inhibition of human recombinant FPPS using GPP and [3H]IPP as substrate incubated with enzyme for 10 mins prior to substrate addition by liquid scintillation counting analysis | Homo sapiens | 14 | single protein format | Scientific Literature | ||
| 14. | ALA3369326 | B | Inhibition of FPPS in human SH-SY5Y cells assessed as blocking of tau metabolism by measuring ratio of tau phosphorylation to total tau level at 100 nM after 24 hrs by ELISA (Rvb = 0.012 no-unit) | Homo sapiens | 14 | cell-based format | Scientific Literature | ||
| 15. | ALA3369327 | A | Cytotoxicity against human SH-SY5Y cells assessed as LDH release after 48 hrs (Rvb = 0%) | Homo sapiens | 14 | cell-based format | Scientific Literature |
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