| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3119334 | F | Antituberculosis activity against multidrug-resistant Mycobacterium tuberculosis LAM1 assessed as growth inhibition at 1 to 5 ug/ml measured everyday by BACTEC assay | Mycobacterium tuberculosis | 1 | organism-based format | Scientific Literature | ||
| 2. | ALA3116777 | F | Antituberculosis activity against Mycobacterium tuberculosis H37Rv expressing lux gene infected in mouse J774A1 cells assessed as inhibition of bacterial replication at 3.13 ug/ml after 4 days by luminometry analysis | Mycobacterium tuberculosis | 1 | organism-based format | Scientific Literature | ||
| 3. | ALA3116778 | F | Antituberculosis activity against Mycobacterium tuberculosis H37Rv expressing lux gene infected in mouse J774A1 cells assessed as inhibition of bacterial replication at 1.56 ug/ml after 4 days by luminometry analysis | Mycobacterium tuberculosis | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA3116780 | T | Genotoxicity in mouse J774A1 cells assessed as ratio of genomic DNA present in tail and head at 0.1 to 10 ug/ml after 24 hrs by comet assay | Mus musculus | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA3116781 | T | Genotoxicity in Salmonella typhimurium Cytox (pr1) expressing lux operon assessed as activation of SOS operon at 0.1 to 10 ug/ml measured for 4 hrs with 5 mins interval by vitotox assay in presence of S9 fraction | Salmonella enterica subsp. enterica serovar Typhimurium | 3 | organism-based format | Scientific Literature | ||
| 6. | ALA3116782 | T | Genotoxicity in Salmonella typhimurium Cytox (pr1) expressing lux operon assessed as activation of SOS operon at 0.1 to 10 ug/ml measured for 4 hrs with 5 mins interval by vitotox assay in absence of S9 fraction | Salmonella enterica subsp. enterica serovar Typhimurium | 3 | organism-based format | Scientific Literature | ||
| 7. | ALA3116783 | T | Genotoxicity in Salmonella typhimurium T104 expressing lux operon assessed as activation of SOS operon at 0.1 to 10 ug/ml measured for 4 hrs with 5 mins interval by vitotox assay in presence of S9 fraction | Salmonella enterica subsp. enterica serovar Typhimurium | 3 | organism-based format | Scientific Literature | ||
| 8. | ALA3116784 | T | Genotoxicity in Salmonella typhimurium T104 expressing lux operon assessed as activation of SOS operon at 0.1 to 10 ug/ml measured for 4 hrs with 5 mins interval by vitotox assay in absence of S9 fraction | Salmonella enterica subsp. enterica serovar Typhimurium | 3 | organism-based format | Scientific Literature | ||
| 9. | ALA3116785 | F | Antituberculosis activity against Mycobacterium ulcerans 1615 expressing lux gene assessed as inhibition of bacterial replication after 6 days by luminometry analysis | Mycobacterium ulcerans | 3 | assay format | Scientific Literature | ||
| 10. | ALA3116786 | F | Antituberculosis activity against Mycobacterium avium ssp. paratuberculosis ATCC 19698 expressing lux gene assessed as inhibition of bacterial replication after 6 days by luminometry analysis | Mycobacterium avium subsp. paratuberculosis | 3 | organism-based format | Scientific Literature | ||
| 11. | ALA3116787 | F | Antituberculosis activity against Mycobacterium avium ssp. avium ATCC 15769 expressing lux gene assessed as inhibition of bacterial replication after 6 days by luminometry analysis | Mycobacterium avium subsp. avium | 3 | assay format | Scientific Literature | ||
| 12. | ALA3116788 | F | Antituberculosis activity against Mycobacterium bovis AN5 expressing lux gene assessed as inhibition of bacterial replication after 6 days by luminometry analysis | Mycobacterium tuberculosis variant bovis | 3 | organism-based format | Scientific Literature | ||
| 13. | ALA3116789 | F | Antituberculosis activity against Mycobacterium tuberculosis H37Rv expressing lux gene assessed as inhibition of bacterial replication after 6 days by luminometry analysis | Mycobacterium tuberculosis | 3 | organism-based format | Scientific Literature | ||
| 14. | ALA3116790 | F | Antituberculosis activity against Mycobacterium tuberculosis H37Rv ATCC 27294 assessed as inhibition of bacterial replication at < 10 ug/ml after 6 days by luminometry analysis relative to control | Mycobacterium tuberculosis | 3 | organism-based format | Scientific Literature | ||
| 15. | ALA3116791 | T | Selectivity index, ratio of IC50 for mouse J774A1 cells to IC50 for Mycobacterium tuberculosis H37Rv expressing pSMT1 | 16 | cell-based format | Scientific Literature | |||
| 16. | ALA3116792 | A | Cytotoxicity against mouse J774A1 cells after 24 hrs by neutral red uptake assay | Mus musculus | 16 | cell-based format | Scientific Literature | ||
| 17. | ALA3116974 | F | Antituberculosis activity against Mycobacterium tuberculosis H37Rv ATCC 27294 assessed as inhibition of bacterial replication after 6 days by luminometry analysis | Mycobacterium tuberculosis | 16 | organism-based format | Scientific Literature |
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