| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3119081 | P | Solubility of the compound in phosphate buffered saline under neutral condition | 4 | small-molecule physicochemical format | Scientific Literature | |||
| 2. | ALA3119264 | P | Solubility of the compound in phosphate buffered saline under acidic condition | 4 | small-molecule physicochemical format | Scientific Literature | |||
| 3. | ALA3119267 | T | Toxicity in Swiss mouse assessed as swollen conjuctiva of eyes at 4 to 8 mg/kg | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA3119268 | T | Toxicity in Swiss mouse assessed as orange urine at 4 to 8 mg/kg | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA3119269 | T | Toxicity in Swiss mouse assessed as difficulty in movement at 4 to 8 mg/kg | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA3119270 | T | Toxicity in Swiss mouse assessed as whole body tremor at 4 to 8 mg/kg | Mus musculus | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA3119278 | A | Intrinsic clearance in mouse liver microsomes at 1 uM after 60 mins by LC-MS/MS analysis | Mus musculus | 4 | microsome format | Scientific Literature | ||
| 8. | ALA3119279 | A | Intrinsic clearance in human liver microsomes at 1 uM after 60 mins by LC-MS/MS analysis | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 9. | ALA3119280 | A | Half life in mouse liver microsomes at 1 uM after 60 mins by LC-MS/MS analysis | Mus musculus | 4 | microsome format | Scientific Literature | ||
| 10. | ALA3119281 | A | Half life in human liver microsomes at 1 uM after 60 mins by LC-MS/MS analysis | Homo sapiens | 4 | assay format | Scientific Literature | ||
| 11. | ALA3119282 | F | Selectivity ratio of IC50 for chloroquine-sensitive Plasmodium falciparum 3D7 to IC50 for chloroquine and mefloquine-resistant Plasmodium falciparum Dd2 | 4 | assay format | Scientific Literature | |||
| 12. | ALA3119283 | U | Selectivity index, ratio of IC50 for human NFF to IC50 for chloroquine and mefloquine-resistant Plasmodium falciparum Dd2 | 6 | assay format | Scientific Literature | |||
| 13. | ALA3119284 | U | Selectivity index, ratio of IC50 for human NFF to IC50 for chloroquine-sensitive Plasmodium falciparum 3D7 | 6 | assay format | Scientific Literature | |||
| 14. | ALA3119285 | A | Cytotoxicity against human NFF after 72 hrs by SRB assay | Homo sapiens | 6 | cell-based format | Scientific Literature | ||
| 15. | ALA3119286 | F | Antimalarial activity against chloroquine and mefloquine-resistant Plasmodium falciparum Dd2 assessed as [3H]-hypoxanthine incorporation after 48 hrs by liquid scintillation counting analysis | Plasmodium falciparum | 6 | assay format | Scientific Literature | ||
| 16. | ALA3119287 | F | Antimalarial activity against chloroquine-sensitive Plasmodium falciparum 3D7 assessed as [3H]-hypoxanthine incorporation after 48 hrs by liquid scintillation counting analysis | Plasmodium falciparum | 6 | organism-based format | Scientific Literature |
The page will load shortly, Thanks for your patience!