| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3116764 | A | Plasma concentration in Sprague-Dawley rat at 4.8 mg/kg, iv administered as bolus dose measured after 1 hr by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 2. | ALA3116765 | A | Drug excretion in Sprague-Dawley rat bile at 5 mg/kg, iv administered as bolus dose measured after 2 hrs by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 3. | ALA3116935 | A | Drug excretion in Sprague-Dawley rat urine at 4.8 mg/kg, iv administered as bolus dose measured after 24 hrs by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA3116936 | A | Volume of distribution at steady state in Sprague-Dawley rat at 4.8 mg/kg, iv administered as bolus dose by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA3116937 | A | Initial plasma concentration in Sprague-Dawley rat at 4.8 mg/kg, iv administered as bolus dose by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA3116938 | A | Half life in Sprague-Dawley rat at 4.8 mg/kg, iv administered as bolus dose by LC-MS/MS analysis | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA3116939 | B | Inhibition of human ERG expressed in CHO cells by patch clamp assay | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA3116940 | A | Induction of CYP3A4 activity (unknown origin) relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 9. | ALA3116941 | A | Induction of CYP1A2 activity (unknown origin) relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 10. | ALA3116942 | A | Induction of CYP1A1 activity (unknown origin) relative to control | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 11. | ALA3116943 | A | Inhibition of CYP3A4 (unknown origin) after 10 to 30 mins | Homo sapiens | 1 | single protein format | Scientific Literature | ||
| 12. | ALA3116944 | A | Permeability across human Caco2 cells | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 13. | ALA3116945 | A | Metabolic stability in rat plasma at 100 ng/mL measured after 4 hrs | Rattus norvegicus | 1 | cell-free format | Scientific Literature | ||
| 14. | ALA3116946 | A | Metabolic stability in mouse plasma at 100 ng/mL measured after 4 hrs | Mus musculus | 1 | cell-free format | Scientific Literature | ||
| 15. | ALA3116947 | A | Drug metabolism in Swiss CD-1 mouse liver microsomes at 5 uM after 20 mins | Mus musculus | 1 | microsome format | Scientific Literature | ||
| 16. | ALA3116948 | A | Metabolic stability in human plasma at 100 ng/mL measured after 4 hrs | Homo sapiens | 1 | cell-free format | Scientific Literature | ||
| 17. | ALA3116949 | A | Drug metabolism in Sprague-Dawley rat liver microsomes at 5 uM after 20 mins | Rattus norvegicus | 1 | assay format | Scientific Literature | ||
| 18. | ALA3116950 | A | Drug metabolism in human liver microsomes at 5 uM after 20 mins | Homo sapiens | 1 | assay format | Scientific Literature | ||
| 19. | ALA3116951 | P | Solubility of the compound at pH 7.4 at 25 degC | 1 | small-molecule physicochemical format | Scientific Literature | |||
| 20. | ALA3116952 | P | Lipophilicity, log D of the compound at pH 7.4 at 25 degC | 1 | small-molecule physicochemical format | Scientific Literature |
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