| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3119481 | B | Inhibition of Escherichia coli GroEL/GroES-ATPase activity expressed in Escherichia coli DH5alpha/BL21 (DE3) assessed as inhibition of denatured MDH refolding preincubated for 10 mins followed by ATP addition measured after 2 hrs by fluorescence based assay | Escherichia coli | 36 | assay format | Scientific Literature | ||
| 2. | ALA3119482 | B | Inhibition of pig heart MDH using chaperonin as substrate | Sus scrofa | 36 | assay format | Scientific Literature | ||
| 3. | ALA3119483 | B | Inhibition of Escherichia coli GroEL/GroES expressed in Escherichia coli DH5alpha/BL21 (DE3) assessed as inhibition of denatured MDH refolding preincubated for 10 mins followed by ATP addition measured after 2 hrs by fluorescence based assay | Escherichia coli | 36 | assay format | Scientific Literature | ||
| 4. | ALA3813260 | B | Inhibition of Escherichia coli GroEL/GroES using Escherichia coli GroEL expressed in Escherichia coli DH5alpha cells and Escherichia coli GroES expressed in Escherichia coli BL21(DE3) cells assessed as inhibition of denatured rhodanese refolding by measuring reduction in thiocyanate production incubated for 60 mins by micro plate reader analysis | Escherichia coli | 22 | cell-based format | Scientific Literature | ||
| 5. | ALA3813261 | B | Inhibition of Escherichia coli GroEL/GroES using Escherichia coli GroEL expressed in Escherichia coli DH5alpha cells and Escherichia coli GroES expressed in Escherichia coli BL21(DE3) cells assessed as reduction in native refolded rhodanese-mediated thiocyanate production by micro plate reader analysis | Escherichia coli | 22 | cell-based format | Scientific Literature | ||
| 6. | ALA3813262 | B | Inhibition of Escherichia coli GroEL/GroES using Escherichia coli GroEL expressed in Escherichia coli DH5alpha cells and Escherichia coli GroES expressed in Escherichia coli BL21(DE3) cells assessed as reduction in pig heart native refolded MDH-mediated NADH production by micro plate reader analysis | Escherichia coli | 22 | cell-based format | Scientific Literature | ||
| 7. | ALA3813263 | B | Inhibition of Escherichia coli GroEL/GroES using Escherichia coli GroEL expressed in Escherichia coli DH5alpha cells and Escherichia coli GroES expressed in Escherichia coli BL21(DE3) cells assessed as inhibition of denatured pig heart MDH refolding by measuring reduction in NADH production incubated for 60 mins by micro plate reader analysis | Escherichia coli | 22 | cell-based format | Scientific Literature | ||
| 8. | ALA3813264 | B | Inhibition of Escherichia coli GroEL/GroES using Escherichia coli GroEL expressed in Escherichia coli DH5alpha cells and Escherichia coli GroES expressed in Escherichia coli BL21(DE3) cells assessed as reduction in denatured pig heart MDH ATPase activity by malachite green dye based assay | Escherichia coli | 22 | cell-based format | Scientific Literature | ||
| 9. | ALA3813265 | F | Antibacterial activity against Escherichia coli DH5alpha assessed as reduction in bacterial growth incubated for 6 to 8 hrs | Escherichia coli | 22 | organism-based format | Scientific Literature | ||
| 10. | ALA3813266 | F | Antibacterial activity against acrB-deficient Escherichia coli MC4100 assessed as reduction in bacterial growth incubated for 6 to 8 hrs | Escherichia coli | 22 | organism-based format | Scientific Literature | ||
| 11. | ALA3813267 | F | Antibacterial activity against Escherichia coli SM101 assessed as reduction in bacterial growth incubated for 12 hrs by UV-Vis spectrophotometric analysis | Escherichia coli | 22 | organism-based format | Scientific Literature | ||
| 12. | ALA3813268 | F | Antibacterial activity against Bacillus subtilis 168 assessed as reduction in bacterial growth incubated for 6 to 8 hrs | Bacillus subtilis | 22 | organism-based format | Scientific Literature | ||
| 13. | ALA3813269 | F | Antibacterial activity against multidrug resistant Enterococcus faecium NCTC 7171 (ATCC 19434) assessed as reduction in bacterial growth incubated for 6 to 8 hrs | Enterococcus faecium | 30 | organism-based format | Scientific Literature | ||
| 14. | ALA3813270 | F | Antibacterial activity against multidrug resistant Staphylococcus aureus subsp. aureus Seattle 1945 (ATCC 25923) assessed as reduction in bacterial growth incubated for 6 to 8 hrs | Staphylococcus aureus | 30 | organism-based format | Scientific Literature | ||
| 15. | ALA3813271 | F | Antibacterial activity against methicillin resistant Staphylococcus aureus subsp. aureus HPV107 (ATCC BAA-44) assessed as reduction in bacterial growth incubated for 6 to 8 hrs | Staphylococcus aureus | 30 | organism-based format | Scientific Literature | ||
| 16. | ALA3813272 | B | Inhibition of human HSP60/HSP10 expressed in Escherichia coli Rosetta2(DE3) cells assessed as inhibition of denatured pig heart MDH refolding by measuring reduction in NADH production incubated for 60 mins by micro plate reader analysis | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
| 17. | ALA3813273 | B | Inhibition of human HSP60/HSP10 expressed in Escherichia coli Rosetta2(DE3) cells assessed as reduction in denatured pig heart MDH ATPase activity by malachite green dye based assay | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
| 18. | ALA3813274 | A | Cytotoxicity against human THLE3 cells assessed as reduction in cell viability after 48 hrs by alamar blue assay | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
| 19. | ALA3813275 | A | Cytotoxicity against HEK293 cells assessed as reduction in cell viability after 48 hrs by alamar blue assay | Homo sapiens | 22 | cell-based format | Scientific Literature | ||
| 20. | ALA3813406 | F | Antibacterial activity against multidrug resistant Klebsiella pneumoniae subsp. pneumoniae NCTC 9633 (ATCC 13883) assessed as reduction in bacterial growth incubated for 6 to 8 hrs | Klebsiella pneumoniae subsp. pneumoniae | 30 | organism-based format | Scientific Literature |
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