| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3116568 | B | Agonist activity at TLR7/TLR8 in human PBMC assessed as induction of IFN-alpha production at 22.5 uM after 24 hrs by ELISA | Homo sapiens | 4 | protein format | Scientific Literature | ||
| 2. | ALA3116569 | B | Agonist activity at TLR7/TLR8 in human PBMC assessed as induction of IFN-gamma production at 22.5 uM after 24 hrs by flow cytometric analysis | Homo sapiens | 4 | protein format | Scientific Literature | ||
| 3. | ALA3116570 | B | Agonist activity at TLR7/TLR8 in human PBMC assessed as induction of TNF-alpha production at 22.5 uM after 24 hrs by flow cytometric analysis | Homo sapiens | 5 | protein format | Scientific Literature | ||
| 4. | ALA3116704 | B | Agonist activity at TLR7/TLR8 in C57BL/6 mouse BMDC assessed as induction of IL-10 production at 30 uM after 3 days by flow cytometric analysis | Mus musculus | 15 | protein format | Scientific Literature | ||
| 5. | ALA3116705 | B | Agonist activity at TLR7/TLR8 in C57BL/6 mouse BMDC assessed as induction of IL-12p40 production at 30 uM after 3 days by flow cytometric analysis | Mus musculus | 15 | protein format | Scientific Literature | ||
| 6. | ALA3116706 | B | Agonist activity at TLR7/TLR8 in C57BL/6 mouse BMDC assessed as induction of IL-1beta production at 30 uM after 3 days by flow cytometric analysis | Mus musculus | 15 | protein format | Scientific Literature | ||
| 7. | ALA3116707 | B | Agonist activity at TLR7/TLR8 in C57BL/6 mouse BMDC assessed as induction of TNF-alpha production at 30 uM after 3 days by flow cytometric analysis | Mus musculus | 15 | protein format | Scientific Literature | ||
| 8. | ALA3116708 | B | Agonist activity at human TLR-8 expressed in HEK293 cells after 24 hrs by SEAP reporter gene assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
| 9. | ALA3116709 | B | Agonist activity at human TLR-7 expressed in HEK293 cells after 24 hrs by SEAP reporter gene assay | Homo sapiens | 15 | cell-based format | Scientific Literature | ||
| 10. | ALA4136300 | B | Agonist activity at human TLR7 expressed in HEK cells after 8 to 12 hrs by NFkappaB/SEAP reporter gene assay | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
| 11. | ALA4136302 | B | Agonist activity at human TLR8 expressed in HEK cells after 8 to 12 hrs by NFkappaB/SEAP reporter gene assay | Homo sapiens | 9 | cell-based format | Scientific Literature |
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