# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3124055 | B | Inhibition of Hepatitis C virus genotype 1b NS3/4A protease D168Y mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as substrate incubated for 30 mins prior to substrate addition by time-resolved fluorescence assay | Hepatitis C virus subtype 1b | 25 | assay format | Scientific Literature | ||
2. | ALA3124056 | B | Inhibition of Hepatitis C virus genotype 1b NS3/4A protease A156V mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as substrate incubated for 30 mins prior to substrate addition by time-resolved fluorescence assay | Hepatitis C virus subtype 1b | 25 | assay format | Scientific Literature | ||
3. | ALA3124057 | B | Inhibition of Hepatitis C virus genotype 1b NS3/4A protease A156T mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as substrate incubated for 30 mins prior to substrate addition by time-resolved fluorescence assay | Hepatitis C virus subtype 1b | 25 | assay format | Scientific Literature | ||
4. | ALA3124059 | B | Inhibition of Hepatitis C virus genotype 1b NS3/4A protease R155K mutant assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as substrate incubated for 30 mins prior to substrate addition by time-resolved fluorescence assay | Hepatitis C virus subtype 1b | 25 | assay format | Scientific Literature | ||
5. | ALA3124062 | A | AUC in rat at 5 mg/kg, po | Rattus norvegicus | 8 | organism-based format | Scientific Literature | ||
6. | ALA3124063 | B | Inhibition of Hepatitis C virus genotype 3a NS3/4A protease assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as substrate incubated for 30 mins prior to substrate addition by time-resolved fluorescence assay | Hepatitis C virus subtype 3a | 25 | assay format | Scientific Literature | ||
7. | ALA3124064 | B | Inhibition of Hepatitis C virus genotype 1b NS3/4A protease assessed as substrate cleavage using Ac-C(Eu)DDMEEAbu(COO)ASK(QSY7)-amide as substrate incubated for 30 mins prior to substrate addition by time-resolved fluorescence assay | Hepatitis C virus subtype 1b | 25 | assay format | Scientific Literature |