# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3123279 | A | Therapeutic index, ratio of ED50 for induction of catalepsy to ED50 for antipsychotic activity in po dosed Kunming mouse assessed as reduction in MK801-induced hyperactivity | Mus musculus | 4 | organism-based format | Scientific Literature | ||
2. | ALA3123280 | A | Therapeutic index, ratio of ED50 for induction of catalepsy to ED50 for antipsychotic activity in po dosed Kunming mouse assessed as reversal of apomorphine-induced cage climbing response | Mus musculus | 4 | organism-based format | Scientific Literature | ||
3. | ALA3123281 | T | Toxicity in po dosed Kunming mouse assessed as induction of catalepsy | Mus musculus | 4 | organism-based format | Scientific Literature | ||
4. | ALA3123282 | F | Antipsychotic activity in po dosed Kunming mouse assessed as reduction in MK801-induced hyperactivity compound administered 30 mins prior to MK801 challenge measured for 90 mins post challenge | Mus musculus | 4 | organism-based format | Scientific Literature | ||
5. | ALA3123283 | F | Antipsychotic activity in po dosed Kunming mouse assessed as reversal of apomorphine-induced cage climbing response compound administered 30 mins prior to apomorphine challenge measured for 30 mins post challenge | Mus musculus | 4 | organism-based format | Scientific Literature | ||
6. | ALA3123284 | T | Acute toxicity in po dosed Kunming mouse assessed as survival measured after 24 hrs | Mus musculus | 1 | organism-based format | Scientific Literature | ||
7. | ALA3123285 | B | Displacement of [3H]mepyramine from histamine H1 receptor in guinea pig cerebellum homogenate after 60 mins by liquid scintillation counting | Cavia porcellus | 6 | tissue-based format | Scientific Literature | ||
8. | ALA3123286 | B | Displacement of [3H]7-OH-DPA from dopamine D3 receptor in Sprague-Dawley rat olfactory tubercle homogenate after 60 mins by liquid scintillation counting | Rattus norvegicus | 6 | tissue-based format | Scientific Literature | ||
9. | ALA3123287 | B | Displacement of [3H]spiperone from dopamine D2 receptor in Sprague-Dawley rat striatum homogenate after 30 mins by liquid scintillation counting | Rattus norvegicus | 28 | assay format | Scientific Literature | ||
10. | ALA3123288 | B | Displacement of [3H]Ketanserin from 5HT2A receptor in Sprague-Dawley rat brain cortex homogenate after 30 mins by liquid scintillation counting | Rattus norvegicus | 28 | tissue-based format | Scientific Literature | ||
11. | ALA3123289 | B | Displacement of [3H]8-OH-DPAT from 5HT1A receptor in Sprague-Dawley rat brain cortex homogenate after 30 mins by liquid scintillation counting | Rattus norvegicus | 28 | tissue-based format | Scientific Literature |