| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3123259 | F | Inverse agonist activity at human histamine H3 receptor by [35S]GTPgammaS binding assay | Homo sapiens | 2 | assay format | Scientific Literature | ||
| 2. | ALA3123260 | F | Enhancement of short term memory in rat social recognition memory model assessed as decrease in investigation ratio at 0.03 to 0.3 mg/kg, po | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 3. | ALA3123261 | T | Toxicity in EEG/EMG rat model assessed as EEG activity at 1 to 30 mg/kg, ip | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA3123262 | T | Toxicity in EEG/EMG rat model assessed as sleep rebound at 1 to 30 mg/kg, ip | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA3123263 | T | Toxicity in EEG/EMG rat model assessed as abnormal behavior at 1 to 30 mg/kg, ip | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 6. | ALA3123264 | F | Wake promoting activity in EEG/EMG rat model assessed as cumulative wake time at 30 mg/kg, ip after 7.5 to 18 hrs relative to vehicle-treated control | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 7. | ALA3123265 | F | Wake promoting activity in EEG/EMG rat model assessed as cumulative wake time at 30 mg/kg, ip after 1.5 hrs relative to vehicle-treated control | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 8. | ALA3123266 | F | Wake promoting activity in EEG/EMG rat model assessed as cumulative wake time at 30 mg/kg, ip after 4 hrs (Rvb = 86 +/- 7 mins) | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 9. | ALA3123267 | F | Wake promoting activity in EEG/EMG rat model assessed as cumulative wake time at 10 mg/kg, ip after 4 hrs (Rvb = 86 +/- 7 mins) | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 10. | ALA3123301 | F | Wake promoting activity in EEG/EMG rat model assessed as cumulative wake time at 10 mg/kg, ip after 1.5 hrs relative to vehicle-treated control | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 11. | ALA3123302 | F | Wake promoting activity in EEG/EMG rat model assessed as cumulative wake time at 3 mg/kg, ip after 4 hrs (Rvb = 86 +/- 7 mins) | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 12. | ALA3123303 | F | Wake promoting activity in EEG/EMG rat model assessed as cumulative wake time at 1 mg/kg, ip after 4 hrs (Rvb = 86 +/- 7 mins) | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 13. | ALA3123304 | F | Wake promoting activity in ip dosed EEG/EMG rat model assessed as cumulative wake time after 4 hrs | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 14. | ALA3123305 | A | Ratio of drug uptake in brain to plasma in dog at 5 mg/kg, po after 6 hrs | Canis lupus familiaris | 1 | organism-based format | Scientific Literature | ||
| 15. | ALA3123306 | A | Ratio of drug uptake in brain to plasma in rat at 10 mg/kg, ip after 6 hrs | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 16. | ALA3123307 | A | Oral bioavailability in dog at 3 mg/kg | Canis lupus familiaris | 1 | organism-based format | Scientific Literature | ||
| 17. | ALA3123308 | A | Oral bioavailability in monkey at 3 mg/kg | Macaca mulatta | 1 | organism-based format | Scientific Literature | ||
| 18. | ALA3123309 | A | Oral bioavailability in rat at 5 mg/kg | Rattus norvegicus | 2 | organism-based format | Scientific Literature | ||
| 19. | ALA3123310 | F | In vivo inhibition of histamine H3 receptor in ip dosed rat dipsogenia model assessed as inhibition of RAMH-induced dipsogenia | Rattus norvegicus | 1 | organism-based format | Scientific Literature | ||
| 20. | ALA3123311 | A | Cmax in monkey at 3 mg/kg, po | Macaca mulatta | 1 | organism-based format | Scientific Literature |
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