# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3123937 | T | Toxicity in Swiss mouse assessed as hypothermia at 1 mg/kg, sc | Mus musculus | 2 | ALA3120046 | organism-based format | Scientific Literature | |
2. | ALA3123943 | T | Toxicity in Swiss mouse assessed as lachrymation at 1 mg/kg, sc | Mus musculus | 2 | ALA3120046 | organism-based format | Scientific Literature | |
3. | ALA3123949 | T | Toxicity in Swiss mouse assessed as salivation at 1 mg/kg, sc | Mus musculus | 2 | ALA3120046 | organism-based format | Scientific Literature | |
4. | ALA3123955 | T | Toxicity in Swiss mouse assessed as diarrhea at 1 mg/kg, sc | Mus musculus | 2 | ALA3120046 | organism-based format | Scientific Literature | |
5. | ALA3123970 | A | Sedative activity in sc dosed Swiss mouse assessed as immobility time at 5 mg/kg, sc by open-field test | Mus musculus | 1 | ALA3120046 | organism-based format | Scientific Literature | |
6. | ALA3123976 | F | Antinociceptive activity in Swiss mouse assessed as effect on acetic acid-induced writhing up to 1 mg/kg, sc administered 30 mins prior challenge | Mus musculus | 4 | ALA3120046 | organism-based format | Scientific Literature | |
7. | ALA3123977 | F | Antinociceptive activity in sc dosed Swiss mouse assessed as effect on acetic acid-induced writhing compound administered 30 mins prior challenge | Mus musculus | 6 | ALA3120046 | organism-based format | Scientific Literature | |
8. | ALA3123980 | B | Inhibition of acetylcholinesterase in rat brain homogenate after 15 mins by Ellman assay relative to control | Rattus norvegicus | 12 | ALA3120046 | tissue-based format | Scientific Literature | |
9. | ALA3123981 | B | Inhibition of acetylcholinesterase in rat brain homogenate after 15 mins by Ellman assay | Rattus norvegicus | 12 | ALA3120046 | tissue-based format | Scientific Literature | |
10. | ALA3123982 | B | Intrinsic activity at muscarinic M3 receptor in albino guinea pig ileum assessed as stimulation of electrically-induced response relative to bethanechol | Cavia porcellus | 12 | ALA3120046 | tissue-based format | Scientific Literature | |
11. | ALA3123983 | B | Intrinsic activity at muscarinic M2 receptor in albino guinea pig left atrium assessed as stimulation of electrically-induced response relative to bethanechol | Cavia porcellus | 12 | ALA3120046 | single protein format | Scientific Literature | |
12. | ALA3123984 | B | Intrinsic activity at muscarinic M1 receptor in New Zealand rabbit vas deferens assessed as stimulation of electrically-induced response relative to McN-A-343 | Oryctolagus cuniculus | 12 | ALA3120046 | tissue-based format | Scientific Literature | |
13. | ALA3123985 | B | Agonist activity at muscarinic M3 receptor in albino guinea pig ileum assessed as stimulation of electrically-induced response | Cavia porcellus | 10 | ALA3120046 | tissue-based format | Scientific Literature | |
14. | ALA3123986 | B | Agonist activity at muscarinic M2 receptor in albino guinea pig left atrium assessed as stimulation of electrically-induced response | Cavia porcellus | 10 | ALA3120046 | single protein format | Scientific Literature | |
15. | ALA3124177 | B | Agonist activity at muscarinic M1 receptor in New Zealand rabbit vas deferens assessed as stimulation of electrically-induced response | Oryctolagus cuniculus | 10 | ALA3120046 | tissue-based format | Scientific Literature | |
16. | ALA4257759 | B | Inhibition of equine serum BChE using butyrylthiocholine iodide as substrate pretreated for 4.5 mins followed by substrate addition and measured after 2.5 mins by Ellman's method | Equus caballus | 20 | ALA4257444 | single protein format | Scientific Literature | |
17. | ALA4257760 | B | Inhibition of electric eel AChE using acetylthiocholine iodide as substrate pretreated for 4.5 mins followed by substrate addition and measured after 2.5 mins by Ellman's method | Electrophorus electricus | 18 | ALA4257444 | single protein format | Scientific Literature | |
18. | ALA4257761 | B | Inhibition of human serum BChE using butyrylthiocholine iodide as substrate pretreated for 4.5 mins followed by substrate addition and measured after 2.5 mins by Ellman's method | Homo sapiens | 20 | ALA4257444 | single protein format | Scientific Literature | |
19. | ALA4257762 | B | Inhibition of recombinant human AChE expressed in HEK293 cells using acetylthiocholine iodide as substrate pretreated for 4.5 mins followed by substrate addition and measured after 2.5 mins by Ellman's method | Homo sapiens | 20 | ALA4257444 | cell-based format | Scientific Literature | |
20. | ALA4257764 | A | Cytotoxicity against human HepG2 cells after 72 hrs by alamar blue assay | Homo sapiens | 20 | ALA4257444 | cell-based format | Scientific Literature |