| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3123671 | F | Growth inhibition of PR, ER, HER2-negative human MDA-MB-231 cells at 1 uM after 48 hrs by WST-1 assay in presence of mevalonate | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA3123672 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as necrotic cells at 10 uM after 48 hrs by annexin V/propidium iodide based flow cytometry (Rvb = 4.4 +/-0.4%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 3. | ALA3123673 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as apoptotic cells at 10 uM after 48 hrs by annexin V/propidium iodide based flow cytometry (Rvb = 2.4 +/-0.5%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA3123674 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as viable cells at 10 uM after 48 hrs by annexin V/propidium iodide based flow cytometry (Rvb = 93.2 +/-0.9%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 5. | ALA3123675 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as necrotic cells at 5 uM after 48 hrs by annexin V/propidium iodide based flow cytometry (Rvb = 4.4 +/-0.4%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 6. | ALA3123676 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as apoptotic cells at 5 uM after 48 hrs by annexin V/propidium iodide based flow cytometry (Rvb = 2.4 +/-0.5%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 7. | ALA3123677 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as viable cells at 5 uM after 48 hrs by annexin V/propidium iodide based flow cytometry (Rvb = 93.2 +/-0.9%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 8. | ALA3123678 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as necrotic cells at 1 uM after 48 hrs by annexin V/propidium iodide based flow cytometry (Rvb = 4.4 +/-0.4%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA3123679 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as apoptotic cells at 1 uM after 48 hrs by annexin V/propidium iodide based flow cytometry (Rvb = 2.4 +/-0.5%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 10. | ALA3123680 | F | Induction of apoptosis in human MDA-MB-231 cells assessed as viable cells at 1 uM after 48 hrs by annexin V/propidium iodide based flow cytometry (Rvb = 93.2 +/-0.9%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA3123681 | A | Stability of the compound in human MDA-MB-231 cells assessed as DHA content at 5 uM after 24 hrs by gas chromatography | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3123682 | A | Stability of the compound in mouse serum at 1 mM after 2 hrs by RP-HPLC analysis | Mus musculus | 1 | assay format | Scientific Literature | ||
| 13. | ALA3123683 | F | Downregulation of p21 expression in human PR, ER, HER2-negative human MDA-MB-231 cells at 10 uM after 24 hrs by western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 14. | ALA3123685 | F | Cell cycle arrest in PR, ER, HER2-negative human MDA-MB-231 cells assessed as accumulation at G2/M phase at 10 uM after 30 hrs by flow cytometer (Rvb = 17.1 +/-2.1%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 15. | ALA3123686 | F | Cell cycle arrest in PR, ER, HER2-negative human MDA-MB-231 cells assessed as accumulation at S phase at 10 uM after 30 hrs by flow cytometer (Rvb = 33.1 +/-0.3%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 16. | ALA3123687 | F | Cell cycle arrest in PR, ER, HER2-negative human MDA-MB-231 cells assessed as accumulation at G0/G1 phase at 10 uM after 30 hrs by flow cytometer (Rvb = 49.8 +/-1.5%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 17. | ALA3123688 | F | Cell cycle arrest in PR, ER, HER2-negative human MDA-MB-231 cells assessed as accumulation at G2/M phase at 1 uM after 30 hrs by flow cytometer (Rvb = 17.1 +/-2.1%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 18. | ALA3123689 | F | Cell cycle arrest in PR, ER, HER2-negative human MDA-MB-231 cells assessed as accumulation at S phase at 1 uM after 30 hrs by flow cytometer (Rvb = 33.1 +/-0.3%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 19. | ALA3123690 | F | Cell cycle arrest in PR, ER, HER2-negative human MDA-MB-231 cells assessed as accumulation at G0/G1 phase at 1 uM after 30 hrs by flow cytometer (Rvb = 49.8 +/-1.5%) | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 20. | ALA3123691 | A | Cytotoxicity against human HMEC at 25 uM after 48 hrs by WST-1 assay | Homo sapiens | 1 | cell-based format | Scientific Literature |
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