#	Aladdin ID	Assay Type	Description	Organism	Compounds	Reference	BAO Format	Source
1.	ALA3124490	F	Ratio of IC50 to KD for mGluR5 receptor in sc dosed Sprague-Dawley rat	Rattus norvegicus	1	ALA3120085	organism-based format	Scientific Literature
2.	ALA3124491	F	Binding affinity to mGluR5 receptor in sc dosed Sprague-Dawley rat	Rattus norvegicus	1	ALA3120085	organism-based format	Scientific Literature
3.	ALA3124492	A	Therapeutic index in cynomolgus monkey	Macaca fascicularis	1	ALA3120085	organism-based format	Scientific Literature
4.	ALA3124493	A	Therapeutic index in cynomolgus monkey 50 mg/kg/day, po	Macaca fascicularis	1	ALA3120085	organism-based format	Scientific Literature
5.	ALA3124494	A	Therapeutic index in cynomolgus monkey 150 mg/kg/day, po	Macaca fascicularis	1	ALA3120085	organism-based format	Scientific Literature
6.	ALA3124495	T	Toxicity in cynomolgus monkey assessed as appearance of erythematous skin lesions at <= 150 mg/kg/day, po after 9 days	Macaca fascicularis	1	ALA3120085	organism-based format	Scientific Literature
7.	ALA3124496	A	Therapeutic index in rat at 80 mg/kg, po	Rattus norvegicus	1	ALA3120085	organism-based format	Scientific Literature
8.	ALA3124497	T	Toxicity in rat at <= 100 mg/kg/day, po after 90 days	Rattus norvegicus	1	ALA3120085	organism-based format	Scientific Literature
9.	ALA3124498	A	Therapeutic index in cynomolgus monkey after 24 hrs	Macaca fascicularis	1	ALA3120085	organism-based format	Scientific Literature
10.	ALA3124499	T	Toxicity in cynomolgus monkey at <= 75 mg/kg/day, po after 14 days	Macaca fascicularis	1	ALA3120085	organism-based format	Scientific Literature
11.	ALA3124500	T	Toxicity in rat at <= 80 mg/kg/day, po after 14 days	Rattus norvegicus	1	ALA3120085	organism-based format	Scientific Literature
12.	ALA3124501	F	Modulation of excessive glutamate release in basal ganglia of cynomolgus monkey MPTP-rendered Parkinsonian L-DOPA-induced dyskinesia model	Macaca fascicularis	1	ALA3120085	organism-based format	Scientific Literature
13.	ALA3124502	F	Antiparkinsonian effect in cynomolgus monkey MPTP-rendered Parkinsonian L-DOPA-induced dyskinesia model assessed as reduction in total disability at 0.32 to 1 mg/kg, sc after 6 hrs	Macaca fascicularis	1	ALA3120085	organism-based format	Scientific Literature
14.	ALA3124503	F	Antiparkinsonian effect in cynomolgus monkey MPTP-rendered Parkinsonian L-DOPA-induced dyskinesia model assessed as reduction in dyskinesia at 0.32 to 1 mg/kg, sc after 6 hrs	Macaca fascicularis	1	ALA3120085	organism-based format	Scientific Literature
15.	ALA3124504	A	Therapeutic index in rat after 24 hrs	Rattus norvegicus	1	ALA3120085	organism-based format	Scientific Literature
16.	ALA3124507	F	In vivo mGluR5 receptor occupancy in cynomolgus monkey assessed as inhibition of [18F]FPEB binding administered as iv bolus at 30 mins prior to [18F]FPEB- injection followed by constant infusion for 120 mins by PET analysis	Macaca fascicularis	1	ALA3120085	organism-based format	Scientific Literature
17.	ALA3124508	T	Toxicity in cynomolgus monkey assessed as delayed-type immune-mediated type 4 hypersensitivity at <= 150 mg/kg/day, po after 90 days	Macaca fascicularis	1	ALA3120085	organism-based format	Scientific Literature
18.	ALA3124509	F	In vivo mGluR5 receptor occupancy in sc dosed Sprague-Dawley rat brain assessed as inhibition of [3H]MPEPy binding after 60 mins by liquid scintillation counting analysis	Rattus norvegicus	1	ALA3120085	organism-based format	Scientific Literature
19.	ALA3124510	A	Half life in monkey	Macaca mulatta	1	ALA3120085	organism-based format	Scientific Literature
20.	ALA3124511	A	Oral bioavailability in monkey at 30 mg/kg	Macaca mulatta	1	ALA3120085	organism-based format	Scientific Literature