| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3130437 | B | Inhibition of thymidylate synthase in human 2008 cells assessed as [5-3H]dUMP conversion to dTMP after 30 mins by liquid scintillation counting analysis relative to control | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 2. | ALA3130597 | B | Inhibition of thymidylate synthase in 13-fold cisplatin-resistant human C13 cells assessed as effect on thymidylate synthase mRNA level at 5 uM after 48 hrs by RT-PCR analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 3. | ALA3130598 | B | Inhibition of thymidylate synthase in human 2008 cells assessed as upregulation of thymidylate synthase mRNA level at 5 uM after 48 hrs by RT-PCR analysis | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 4. | ALA3130599 | B | Inhibition of thymidylate synthase in 13-fold cisplatin-resistant human C13 cells assessed as downregulation of DHFR protein level at 5 uM after 48 hrs by Western blotting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 5. | ALA3130600 | B | Inhibition of thymidylate synthase in human 2008 cells assessed as downregulation of DHFR protein level at 5 uM after 48 hrs by Western blotting analysis | Homo sapiens | 2 | cell-based format | Scientific Literature | ||
| 6. | ALA3130603 | B | Inhibition of thymidylate synthase in 13-fold cisplatin-resistant human C13 cells assessed as change in thymidylate synthase protein level at 1 to 5 uM after 48 hrs by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 7. | ALA3130604 | B | Inhibition of thymidylate synthase in human 2008 cells assessed as change in thymidylate synthase protein level at 1 to 5 uM after 48 hrs by Western blotting analysis | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 8. | ALA3130605 | F | Cytotoxicity against 10-fold cisplatin-resistant human A2780C/P cells cell survival at 10 uM after 72 hrs by crystal violet staining-based spectrophotometric analysis relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 9. | ALA3130606 | F | Cytotoxicity against human A2780 cells assessed as cell survival at 10 uM after 72 hrs by crystal violet staining-based spectrophotometric analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 10. | ALA3130607 | F | Cytotoxicity against 13-fold cisplatin-resistant human C13 cells cell survival at 10 uM after 72 hrs by crystal violet staining-based spectrophotometric analysis relative to control | Homo sapiens | 3 | cell-based format | Scientific Literature | ||
| 11. | ALA3130608 | F | Cytotoxicity against human 2008 cells assessed as cell survival at 10 uM after 72 hrs by crystal violet staining-based spectrophotometric analysis relative to control | Homo sapiens | 1 | cell-based format | Scientific Literature | ||
| 12. | ALA3130611 | B | Inhibition of human thymidylate synthase using dUMP as substrate at 100 uM after 1 hr by UV-vis spectrophotometric analysis in presence of mTHF relative to control | Homo sapiens | 17 | single protein format | Scientific Literature | ||
| 13. | ALA3414404 | B | Inhibition of wild-type His-tagged human thymidylate synthase after 1 hr by UV-visible spectrophotometry | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 14. | ALA3411863 | B | Inhibition of His-tagged human thymidylate synthase K47A mutant after 1 hr by UV-visible spectrophotometry | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 15. | ALA3411864 | B | Inhibition of His-tagged human thymidylate synthase F59A mutant after 1 hr by UV-visible spectrophotometry | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 16. | ALA3411865 | B | Inhibition of His-tagged human thymidylate synthase L198A mutant after 1 hr by UV-visible spectrophotometry | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 17. | ALA3411866 | B | Inhibition of His-tagged human thymidylate synthase Y202A mutant after 1 hr by UV-visible spectrophotometry | Homo sapiens | 8 | single protein format | Scientific Literature | ||
| 18. | ALA4234617 | F | Downregulation of TRAP1 protein levels in human IGROV1 cells by Western blot analysis | Homo sapiens | 2 | cell-based format | Scientific Literature |
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