# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3128641 | A | Solubility of the compound in fasted state stimulated intestinal fluid at pH 6.5 | 7 | assay format | Scientific Literature | |||
2. | ALA3128642 | P | Solubility of the compound at pH 7 | 7 | small-molecule physicochemical format | Scientific Literature | |||
3. | ALA3128643 | P | Lipophilicity, log D of the compound by HPLC method | 7 | small-molecule physicochemical format | Scientific Literature | |||
4. | ALA3128659 | A | Clearance in human hepatocytes | Homo sapiens | 10 | cell-based format | Scientific Literature | ||
5. | ALA3128660 | A | Clearance in monkey hepatocytes | Macaca mulatta | 10 | cell-based format | Scientific Literature | ||
6. | ALA3128661 | A | Clearance in rat hepatocytes | Rattus norvegicus | 10 | cell-based format | Scientific Literature | ||
7. | ALA3128662 | A | AUC (0 to 6 hrs) in Sprague-Dawley rat at 10 mg/kg, po | Rattus norvegicus | 10 | organism-based format | Scientific Literature | ||
8. | ALA3128665 | F | Antagonist activity at human CRTH2 receptor expressed in HEK cells assessed as inhibition of forskolin-induced cAMP formation preincubated for 10 mins followed by forskolin challenge measured after 10 to 60 mins by ELISA assay | Homo sapiens | 17 | cell-based format | Scientific Literature | ||
9. | ALA3128666 | F | Antagonist activity at human CRTH2 receptor expressed in CHO-1 cells assessed as inhibition of PGD2-induced Ca2+ flux preincubated for 30 mins followed by PGD2 challenge measured after 60 mins by chemiluminescence assay | Homo sapiens | 28 | cell-based format | Scientific Literature |