# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3132229 | F | Anticonvulsant activity in Sprague-Dawley rat hippocampus CA1 pyramidal neurons assessed as suppression of action potential firing frequency at 10 uM by voltage-clamp electrophysiology relative to control | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
2. | ALA3132230 | F | Anticonvulsant activity in Sprague-Dawley rat hippocampus CA1 pyramidal neurons assessed as suppression of EPSC amplitude at 10 uM at -60mV holding potential measured 15 to 20 mins post compound washout by voltage-clamp electrophysiology | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
3. | ALA3132231 | F | Anticonvulsant activity in Sprague-Dawley rat hippocampus CA1 pyramidal neurons assessed as suppression of EPSC amplitude at 10 uM at -60mV holding potential by voltage-clamp electrophysiology relative to control | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
4. | ALA3132232 | F | Anticonvulsant activity in Sprague-Dawley rat hippocampus CA1 pyramidal neurons assessed as suppression of EPSC amplitude at 10 uM by voltage-clamp electrophysiology in presence of GABA transaminase inhibitor vigabatrin | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
5. | ALA3132414 | F | Anticonvulsant activity in Sprague-Dawley rat hippocampus CA1 pyramidal neurons assessed as suppression of EPSC amplitude at 10 uM by voltage-clamp electrophysiology in presence of GABA-B receptor antagonist CGP55845 | Rattus norvegicus | 2 | cell-based format | Scientific Literature | ||
6. | ALA3132415 | F | Anticonvulsant activity in Sprague-Dawley rat hippocampus assessed as inhibition of population spike amplitude at 10 uM preincubated for 6 mins followed by compound washout measured after 10 mins by blind patch-clamp technique | Rattus norvegicus | 10 | tissue-based format | Scientific Literature | ||
7. | ALA3132416 | F | Anticonvulsant activity in Sprague-Dawley rat hippocampus assessed as inhibition of population spike amplitude preincubated for 6 mins followed by compound washout measured after 10 mins by blind patch-clamp technique | Rattus norvegicus | 3 | tissue-based format | Scientific Literature | ||
8. | ALA3132417 | F | Anticonvulsant activity in Sprague-Dawley rat hippocampus assessed as inhibition of population spike amplitude at >= 100 uM preincubated for 6 mins followed by compound washout measured after 10 mins by blind patch-clamp technique | Rattus norvegicus | 10 | tissue-based format | Scientific Literature | ||
9. | ALA3132418 | F | Anticonvulsant activity in CF1 mouse at <100 mg/kg, ip after 30 mins | Mus musculus | 2 | organism-based format | Scientific Literature |