# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3130970 | T | Selectivity index, ratio of CC50 for HOS cells to EC50 for wild-type Human immunodeficiency virus 1 | 7 | ALA3124837 | cell-based format | Scientific Literature | ||
2. | ALA3130971 | F | Antiviral activity against Human immunodeficiency virus 1 harboring integrase G140S/Q148H double mutant infected in HOS cells preincubated for 3 hrs followed by viral infection measured after 48 hrs by luciferase reporter gene assay | Human immunodeficiency virus 1 | 5 | ALA3124837 | organism-based format | Scientific Literature | |
3. | ALA3130972 | F | Antiviral activity against Human immunodeficiency virus 1 harboring integrase N155H mutant infected in HOS cells preincubated for 3 hrs followed by viral infection measured after 48 hrs by luciferase reporter gene assay | Human immunodeficiency virus 1 | 7 | ALA3124837 | organism-based format | Scientific Literature | |
4. | ALA3130973 | F | Antiviral activity against Human immunodeficiency virus 1 harboring integrase Y143R mutant infected in HOS cells preincubated for 3 hrs followed by viral infection measured after 48 hrs by luciferase reporter gene assay | Human immunodeficiency virus 1 | 7 | ALA3124837 | organism-based format | Scientific Literature | |
5. | ALA3132332 | A | Cytotoxicity against HOS cells assessed as reduction in ATP level after 48 hrs by luciferase reporter gene assay | Homo sapiens | 7 | ALA3124837 | cell-based format | Scientific Literature | |
6. | ALA3132334 | B | Inhibition of HIV-1 integrase-mediated strand transfer activity using [32P]-labeled oligonucleotide as substrate after 2 hrs by densitometric analysis | Human immunodeficiency virus 1 | 14 | ALA3124837 | single protein format | Scientific Literature | |
7. | ALA3132335 | B | Inhibition of HIV-1 integrase-mediated 3'-processing activity using [32P]-labeled oligonucleotide as substrate after 2 hrs by densitometric analysis | Human immunodeficiency virus 1 | 14 | ALA3124837 | single protein format | Scientific Literature | |
8. | ALA3132336 | F | Antiviral activity against wild-type Human immunodeficiency virus 1 infected in HOS cells preincubated for 3 hrs followed by viral infection measured after 48 hrs by luciferase reporter gene assay | Human immunodeficiency virus 1 | 7 | ALA3124837 | organism-based format | Scientific Literature | |
9. | ALA5237320 | B | Inhibition of HIV-1 integrase strand transfer activity | Human immunodeficiency virus | 10 | ALA5236553 | single protein format | Scientific Literature |