| # | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
|---|---|---|---|---|---|---|---|---|---|
| 1. | ALA3130961 | F | Ratio of raltegravir EC50 to compound EC50 for Human immunodeficiency virus 1 harboring integrase E138K/Q148K double mutant | Human immunodeficiency virus 1 | 1 | organism-based format | Scientific Literature | ||
| 2. | ALA3130962 | F | Ratio of raltegravir EC50 to compound EC50 for Human immunodeficiency virus 1 harboring integrase G140S/Q148H double mutant | Human immunodeficiency virus 1 | 1 | organism-based format | Scientific Literature | ||
| 3. | ALA3130963 | F | Ratio of raltegravir EC50 to compound EC50 for Human immunodeficiency virus 1 harboring integrase Y143R mutant | Human immunodeficiency virus 1 | 1 | organism-based format | Scientific Literature | ||
| 4. | ALA3130964 | F | Ratio of raltegravir EC50 to compound EC50 for Human immunodeficiency virus 1 harboring integrase N155H mutant | Human immunodeficiency virus 1 | 1 | organism-based format | Scientific Literature | ||
| 5. | ALA3130965 | F | Ratio of EC50 for Human immunodeficiency virus 1 harboring integrase E138K/Q148K double mutant to EC50 for wild-type Human immunodeficiency virus 1 | Human immunodeficiency virus 1 | 2 | organism-based format | Scientific Literature | ||
| 6. | ALA3130966 | F | Ratio of EC50 for Human immunodeficiency virus 1 harboring integrase G118R mutant to EC50 for wild-type Human immunodeficiency virus 1 | Human immunodeficiency virus 1 | 2 | organism-based format | Scientific Literature | ||
| 7. | ALA3130967 | F | Ratio of EC50 for Human immunodeficiency virus 1 harboring integrase G140S/Q148H double mutant to EC50 for wild-type Human immunodeficiency virus 1 | Human immunodeficiency virus 1 | 3 | organism-based format | Scientific Literature | ||
| 8. | ALA3130968 | F | Ratio of EC50 for Human immunodeficiency virus 1 harboring integrase N155H mutant to EC50 for wild-type Human immunodeficiency virus 1 | Human immunodeficiency virus 1 | 3 | organism-based format | Scientific Literature | ||
| 9. | ALA3130969 | F | Ratio of EC50 for Human immunodeficiency virus 1 harboring integrase Y143R mutant to EC50 for wild-type Human immunodeficiency virus 1 | Human immunodeficiency virus 1 | 3 | organism-based format | Scientific Literature | ||
| 10. | ALA3130970 | T | Selectivity index, ratio of CC50 for HOS cells to EC50 for wild-type Human immunodeficiency virus 1 | 7 | cell-based format | Scientific Literature | |||
| 11. | ALA3130971 | F | Antiviral activity against Human immunodeficiency virus 1 harboring integrase G140S/Q148H double mutant infected in HOS cells preincubated for 3 hrs followed by viral infection measured after 48 hrs by luciferase reporter gene assay | Human immunodeficiency virus 1 | 5 | organism-based format | Scientific Literature | ||
| 12. | ALA3130972 | F | Antiviral activity against Human immunodeficiency virus 1 harboring integrase N155H mutant infected in HOS cells preincubated for 3 hrs followed by viral infection measured after 48 hrs by luciferase reporter gene assay | Human immunodeficiency virus 1 | 7 | organism-based format | Scientific Literature | ||
| 13. | ALA3130973 | F | Antiviral activity against Human immunodeficiency virus 1 harboring integrase Y143R mutant infected in HOS cells preincubated for 3 hrs followed by viral infection measured after 48 hrs by luciferase reporter gene assay | Human immunodeficiency virus 1 | 7 | organism-based format | Scientific Literature | ||
| 14. | ALA3132332 | A | Cytotoxicity against HOS cells assessed as reduction in ATP level after 48 hrs by luciferase reporter gene assay | Homo sapiens | 7 | cell-based format | Scientific Literature | ||
| 15. | ALA3132334 | B | Inhibition of HIV-1 integrase-mediated strand transfer activity using [32P]-labeled oligonucleotide as substrate after 2 hrs by densitometric analysis | Human immunodeficiency virus 1 | 14 | single protein format | Scientific Literature | ||
| 16. | ALA3132335 | B | Inhibition of HIV-1 integrase-mediated 3'-processing activity using [32P]-labeled oligonucleotide as substrate after 2 hrs by densitometric analysis | Human immunodeficiency virus 1 | 14 | single protein format | Scientific Literature | ||
| 17. | ALA3132336 | F | Antiviral activity against wild-type Human immunodeficiency virus 1 infected in HOS cells preincubated for 3 hrs followed by viral infection measured after 48 hrs by luciferase reporter gene assay | Human immunodeficiency virus 1 | 7 | organism-based format | Scientific Literature | ||
| 18. | ALA5237320 | B | Inhibition of HIV-1 integrase strand transfer activity | Human immunodeficiency virus | 10 | single protein format | Scientific Literature |
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