# | Aladdin ID | Assay Type | Description | Organism | Compounds | Reference | BAO Format | Source | |
---|---|---|---|---|---|---|---|---|---|
1. | ALA3130563 | F | Antibacterial activity against drug-sensitive Staphylococcus aureus MTCC 737 assessed as cytoplasmic membrane depolarization at MIC measured up to 12 mins by DiSC3(5) dye-based fluorimetric analysis | Staphylococcus aureus | 1 | organism-based format | Scientific Literature | ||
2. | ALA3130752 | A | Therapeutic index, ratio of HC50 for human erythrocytes to MIC for drug-sensitive Pseudomonas aeruginosa ATCC 4676 | 2 | assay format | Scientific Literature | |||
3. | ALA3130753 | F | Antibacterial activity against drug-sensitive Staphylococcus aureus MTCC 737 assessed as formation of blebs and holes at 10 X MIC after 2 hrs by field-emission scanning electron microscopic analysis | Staphylococcus aureus | 2 | organism-based format | Scientific Literature | ||
4. | ALA3132150 | F | Antibacterial activity against drug-sensitive Escherichia coli MTCC 443 assessed as merging of dead bacteria with each other at 10 X MIC after 2 hrs by field-emission scanning electron microscopic analysis | Escherichia coli | 2 | organism-based format | Scientific Literature | ||
5. | ALA3132151 | F | Antibacterial activity against drug-sensitive Escherichia coli MTCC 443 assessed as disruption of cell membrane at 10 X MIC after 2 hrs by field-emission scanning electron microscopic analysis | Escherichia coli | 2 | organism-based format | Scientific Literature | ||
6. | ALA3132152 | F | Antibacterial activity against drug-sensitive Staphylococcus aureus MTCC 737 assessed as change in cell membrane morphology at 10 X MIC after 1.5 hrs by SYTO and propidium iodide staining-based fluorescence microscopic analysis | Staphylococcus aureus | 2 | organism-based format | Scientific Literature | ||
7. | ALA3132153 | F | Antibacterial activity against drug-sensitive Escherichia coli MTCC 443 assessed as outer cytoplasmic membrane permeabilization at MIC measured up to 10 mins by N-phenylnaphthylamine dye-based fluorescence assay | Escherichia coli | 1 | organism-based format | Scientific Literature | ||
8. | ALA3132154 | F | Antibacterial activity against drug-sensitive Staphylococcus aureus MTCC 737 assessed as inner cytoplasmic membrane permeabilization at MIC measured up to 10 mins by propidium iodide staining-based fluorescence assay | Staphylococcus aureus | 1 | organism-based format | Scientific Literature | ||
9. | ALA3132156 | F | Antibacterial activity against drug-sensitive Escherichia coli MTCC 443 at MIC measured up to 15 mins by DiSC3(5) dye-based fluorimetric analysis | Escherichia coli | 1 | organism-based format | Scientific Literature | ||
10. | ALA3132159 | A | Stability of the compound assessed as trypsin (unknown origin)-mediated drug degradation at 1 mg/ml up to 24 hrs by LC-MS analysis | Homo sapiens | 1 | assay format | Scientific Literature | ||
11. | ALA3132160 | F | Antibacterial activity against drug-sensitive Staphylococcus aureus MTCC 737 preincubated for 3 hrs in 50% human plasma measured after 24 hrs by broth microdilution assay | Staphylococcus aureus | 1 | organism-based format | Scientific Literature | ||
12. | ALA3132161 | F | Bactericidal activity against drug-sensitive Staphylococcus aureus MTCC 737 at 2 X MIC after 24 hrs by time-kill assay | Staphylococcus aureus | 1 | organism-based format | Scientific Literature | ||
13. | ALA3132169 | P | Retention time of the compound by HPLC analysis | 19 | small-molecule physicochemical format | Scientific Literature | |||
14. | ALA3132170 | A | Hemolytic activity in human erythrocytes after 1 hr by spectrophotometric analysis | Homo sapiens | 19 | cell-based format | Scientific Literature | ||
15. | ALA3132171 | F | Antibacterial activity against beta-lactam-resistant Klebsiella pneumoniae ATCC 700603 after 24 hrs by broth microdilution assay | Klebsiella pneumoniae | 19 | organism-based format | Scientific Literature | ||
16. | ALA3132343 | F | Antibacterial activity against vancomycin-resistant Enterococcus faecium ATCC 51559 after 24 hrs by broth microdilution assay | Enterococcus faecium | 19 | organism-based format | Scientific Literature | ||
17. | ALA3132344 | F | Antibacterial activity against methicillin-resistant Staphylococcus aureus ATCC 33591 after 24 hrs by broth microdilution assay | Staphylococcus aureus | 19 | organism-based format | Scientific Literature | ||
18. | ALA3132345 | F | Antibacterial activity against drug-sensitive Pseudomonas aeruginosa ATCC 4676 after 24 hrs by broth microdilution assay | Pseudomonas aeruginosa | 18 | organism-based format | Scientific Literature | ||
19. | ALA3132346 | F | Antibacterial activity against drug-sensitive Escherichia coli MTCC 443 after 24 hrs by broth microdilution assay | Escherichia coli | 18 | organism-based format | Scientific Literature | ||
20. | ALA3132347 | F | Antibacterial activity against drug-sensitive Enterococcus faecium ATCC 19634 after 24 hrs by broth microdilution assay | Enterococcus faecium | 18 | organism-based format | Scientific Literature |